Function and Biosynthesis of Lipids pp 535-546 | Cite as
Essential Fatty Acids: What Level in the Diet is Most Desirable?
Abstract
It has been recognized for many years that certain dietary fatty acids, notably linoleic acid, are required to prevent a variety of deficiency symptoms in animals (Burr, 1942; Holman, 1970). A similar need for these fatty acids in human diets has been established more recently. Deficiency symptoms can be demonstrated in children (Söderhjelm et al, 1970) and have also been seen in adults after prolonged parenteral nutrition with fat-deficient preparations (Collins et al, 1971; Riella et al, 1975). It is estimated that these various deficiency symptoms can be prevented by an intake of essential fatty acids in the range of 1 to 2% of total calories (Holman, 1970).
Keywords
Linoleic Acid Human Milk Essential Fatty Acid Cocoa Butter Total CaloriePreview
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References
- American Medical Association Council on Foods & Nutrition and the Food & Nutrition Board, National Academy of Sciences-National Research Council (1972) J. Amer. Med. Ass. 222, 1647.Google Scholar
- Anderson, T. W. (1973) Lancet 2, 298–302.PubMedCrossRefGoogle Scholar
- Artman, N. R. (1969) in Adv. Lipid Res. (Paoletti, R. & Kritchevsky, D., eds.), vol. 7, pp. 245–330, Academic Press, New York.Google Scholar
- Brown, H. B. (1971) J. Amer. Diet. Ass. 58, 303–311.PubMedGoogle Scholar
- Burr, G. O. (1942) Fed. Proc. 1, 224–233.Google Scholar
- Carroll, K. K. (1975) Cancer Res. 35, 3374–3383.PubMedGoogle Scholar
- Carroll, K. K. & Khor, H. T. (1971) Lipids 6, 415–420.PubMedCrossRefGoogle Scholar
- Carroll, K. K., Hamilton, R.M.G. & MacLeod, G. K. (1973) Lipids 8, 635–640.PubMedCrossRefGoogle Scholar
- Carroll, K. K. & Hamilton, R.M.G. (1975) J. Food Sci. 40, 18–23.CrossRefGoogle Scholar
- Carroll, K. K. & Khor, H. T. (1975) in Progress in Biochemical Pharmacology, (Carroll, K. K., ed.), vol. 10, Lipids and Tumors, pp. 308–353, Karger, Basel.Google Scholar
- Carroll, K. K. & Huff, M. W. (1976) in Proc. Int. Workshop-Conference on Atherosclerosis (Manning, G. W. & Haust, M. D., eds.), Plenum Press, New York, in the press.Google Scholar
- Carroll, K. K., Huff, M. W. & Roberts, D.C.K. (1976) in Abst. IV Int. Symp. on Atherosclerosis, p. 55, Tokyo, Japan.Google Scholar
- Collins, F. D., Sinclair, A. J., Royle, J. P., Coats, D. A., Maynard, A. T. & Leonard, R. F. (1971) Nutr. Metab. 13, 150–167.PubMedCrossRefGoogle Scholar
- Cuthbertson, W.F.J. (1976) Amer. J. Clin. Nutr. 29, 559–568.PubMedGoogle Scholar
- Dam, H. (1971) Amer. J. Med. 51, 596–613.PubMedCrossRefGoogle Scholar
- Dayton, S., Pearce, M. L., Hashimoto, S., Dixon, W. J. & Tomiyasu, U. (1969) Circulation 39-40, Suppl. II, 1–63.Google Scholar
- Dayton, S. & Hashimoto, S. (1976) in Abst. IV Int. Symp. on Atherosclerosis, p. 243, Tokyo, Japan.Google Scholar
- Ederer, F., Leren, P., Turpeinen, O. & Frantz, I. D. Jr. (1971) Lancet 2, 203–206.PubMedCrossRefGoogle Scholar
- Food and Agriculture Organization of the United Nations, Rome (1971)Food Balance Sheets, 1964–66 Average.Google Scholar
- Goalwin, A. & Pomeranze, J. (1962) Arch. Pediat. 79, 58–62.PubMedGoogle Scholar
- Hamilton, R.M.G. & Carroll, K. K. (1976) Atherosclerosis 24, 47–62.PubMedCrossRefGoogle Scholar
- Harman, D. (1971) J. Gerontol. 26, 451–457.PubMedGoogle Scholar
- Harman, D. (1973) Triangle 12, 153–158.PubMedGoogle Scholar
- Hassan, H., Hashim, S. A., Van Itallie, T. B. & Sebrell, W. H. (1966) Amer. J. Clin. Nutr. 19, 147–157.PubMedGoogle Scholar
- Heyden, S. (1975) in The Role of Fats in Human Nutrition (Vergroesen, A. J., ed.), Appendix, pp. 96–113, Academic Press, New York.Google Scholar
- Hirsch, J., Farquhar, J. W., Ahrens, E. H. Jr., Peterson, M. L. & Stoffel, W. (1960) Amer. J. Clin. Nutr. 8, 499–511.PubMedGoogle Scholar
- Holman, R. T. (1970) in Progress in the Chemistry of Fats and Other Lipids (Holman, R. T., ed.), vol. 9, part 5, pp. 607–682, Pergamon Press, Oxford.Google Scholar
- Holman, R. T. (1976) This symposium.Google Scholar
- Horwitt, M. K. (1974) Amer. J. Clin. Nutr. 27, 1182–1193.PubMedGoogle Scholar
- Horwitt, M. K. (1976) Amer. J. Clin. Nutr. 29, 569–578.PubMedGoogle Scholar
- Insull, W. Jr., Land, P. D., Hsi, B. P. & Yoshimura, S. (1969) J. Clin. Invest. 48, 1313–1327.PubMedCrossRefGoogle Scholar
- Jager, F. C. (1975) in The Role of Fats in Human Nutrition (Vergroesen, A. J., ed.), pp. 381–432, Academic Press, New York.Google Scholar
- Jelliffe, D. B. & Jelliffe, E.F.P. (1971) Amer. J. Clin. Nutr. 24, 1013–1024.PubMedGoogle Scholar
- Johnson, L., Schaffer, D. & Boggs, T. R. Jr., (1974) Amer. J. Clin. Nutr. 27, 1158–1173.PubMedGoogle Scholar
- Jones, R. J. (1974) J. Amer. Oil Chem. Soc. 51, 251–254.CrossRefGoogle Scholar
- Kinsell, L. W. (1963) in Progress in the Chemistry of Fats and Other Lipids (Holman, R. T., Lundberg, W. O. & Malkin, T., eds.), vol. 6, pp. 137–170, Pergamon Press, Oxford.Google Scholar
- Leren, P. (1970) Circulation 42, 935–942.PubMedCrossRefGoogle Scholar
- Lofland, H. B. (1975) Amer. J. Pathol. 79, 619–622.Google Scholar
- Lofland, H. B., Bullock, B. C. & Clarkson, T. B. (1975) Fed. Proc. 34, 862.Google Scholar
- Macy, I. G. & Kelly, H. J. (1961) in Milk; The Mammary Gland and its Secretion (Kon, S. K. & Cowie, A. T., eds.), vol. II, pp. 265–304, Academic Press, New York.Google Scholar
- Miettinen, M., Turpeinen, O., Karvonen, M. J., Elosuo, R. & Paavilainen, E. (1972) Lancet 2, 835–838.PubMedCrossRefGoogle Scholar
- Morris, J. N. et al (1968) Lancet 2, 693–700.Google Scholar
- Pearce, M. L. & Dayton, S. (1971) Lancet 1, 464–467.PubMedCrossRefGoogle Scholar
- Pinckney, E. R. (1973a) Amer. Heart J. 85, 723–726.PubMedCrossRefGoogle Scholar
- Pinckney, E. R. (1973b) Med. Counterpoint 5, 53–71.Google Scholar
- Portman, O. W., Osuga, T. & Tanaka, N. (1975) in Adv. Lipid Res. (Paoletti, R. & Kritchevsky, D., eds.), vol. 13, pp. 135–194, Academic Press, New York.Google Scholar
- Reddy, B. S., Narisawa, T., Maronpot, R., Weisburger, J. H. & Wynder, E. L. (1975) Cancer Res. 35, 3421–3426.PubMedGoogle Scholar
- Report of the Advisory Panel of the British Committee on Medical Aspects of Food Policy (Nutrition) on Diet in relation to Cardiovascular and Cerebrovascular Disease (1974). Her Majesty’s Stationery Office, London. Reproduced (1975) in Nutrition Today 10(1), 16-18, 24-27.Google Scholar
- Riella, M. C., Broviac, J. W., Wells, M. & Scribner, B. H. (1975) Ann. Intern. Med. 83, 786–789.PubMedGoogle Scholar
- Rinzler, S. H. (1968) Bull. N. Y. Acad. Med. 44, 936–949.PubMedGoogle Scholar
- Rose, G., Blackburn, H., Keys, A., Taylor, H. L., Kannel, W. B., Paul, O., Reid, D. D. & Stamler, J. (1974) Lancet 1, 181–183.PubMedCrossRefGoogle Scholar
- Schubert, W. K. (1973) Amer. J. Cardiol. 31, 581–587.PubMedCrossRefGoogle Scholar
- Söderhjelm, L., Wiese, H. F. & Holman, R. T. (1970) in Progress in the Chemistry of Fats and Other Lipids (Holman, R. T., ed.), vol. 9, part 4, pp. 555–585, Pergamon Press, Oxford.Google Scholar
- Sturdevant, R.A.L., Pearce, M. L., & Dayton, S. (1973) N. Engl. J. Med. 288, 24–27.PubMedCrossRefGoogle Scholar
- Sweeney, M. J., Etteldorf, J. N., Dobbins, W. T., Somervill, B., Fischer, R. & Ferrell, C. (1961) Pediatrics 27, 765–771.PubMedGoogle Scholar
- Tannenbaum, A. (1959) in The Physiopathology of Cancer (Homburger, F., ed.), 2nd edn., pp. 517–562, Hoeber-Harper, New York.Google Scholar
- Tannenbaum, A. & Silverstone, H. (1957) in Cancer (Raven, R. W., ed.), vol. 1, pp. 306–334, Butterworth, London.Google Scholar
- Tappel, A. L. (1972) Ann. N. Y. Acad. Sci. 203, 12–28.PubMedCrossRefGoogle Scholar
- Vergroesen, A. J. (1972) Proc. Nutr. Soc. 31, 323–329.PubMedCrossRefGoogle Scholar
- Vergroesen, A. J. & Gottenbos, J. J. (1975) in The Role of Fats in Human Nutrition (Vergroesen, A. J., ed.), pp. 1–41, Academic Press, New York.Google Scholar
- West, C. E. & Redgrave, T. G. (1974) Search 5, 90–94.Google Scholar
- Witting, L. A. (1970) in Progress in The Chemistry of Fats and Other Lipids (Holman, R. T., ed.), vol. 9, part 4, pp. 517–553, Pergamon Press, Oxford.Google Scholar
- Witting, L. A. (1972) Ann. N. Y. Acad. Sci. 203, 192–198.PubMedCrossRefGoogle Scholar