Effects of Gonadal Hormones on Plasma Renin Activity and Aldosterone Excretion Rate

  • M. G. Crane
  • J. J. Harris


We have reported elsewhere (1) that the administration of ethinyl estradiol increased plasma renin activity (PRA) and aldosterone excretion rate. We were led to make these observations because of the findings of a markedly increased PRA in a normal subject who was taking Orthonovum for contraceptive purposes. Her PRA decreased to normal after the oral contraceptive was discontinued.


Oral Contraceptive Plasma Renin Activity Oral Contraceptive Pill Medroxyprogesterone Acetate Ethinyl Estradiol 
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Copyright information

© Plenum Press, New York 1969

Authors and Affiliations

  • M. G. Crane
    • 1
  • J. J. Harris
    • 1
  1. 1.Department of MedicineLoma Linda UniversityLoma LindaUSA

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