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Coronaviruses pp 391-398 | Cite as

Characterization of Mouse Hepatitis Virus-Reactive T Cell Clones

  • Shigeru Kyuwa
  • Kenjiro Yamaguchi
  • Masanori Hayami
  • Kosaku Fujiwara
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 218)

Abstract

Mouse hepatitis virus (MHV) is a member of the family Coronaviridae and known to induce various types of disease, hepatitis, enteritis and encephalitis in mice depending upon the host strain, age, and immune status1. Using nude or immunomodulated mice, T cell-mediated immunity in MHV infections was suggested to play an important role.2, 3 By the adoptive transfer of spleen cells from immune euthymic mice the growth of MHV in the recipient nude mice was inhibited, and the transfer effect was abolished by treating immune spleen cells with anti-BAT serum and complement3.

Keywords

Cell Clone Spleen Cell Stimulator Cell Mouse Hepatitis Virus Hind Footpad 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Shigeru Kyuwa
    • 1
  • Kenjiro Yamaguchi
    • 1
  • Masanori Hayami
    • 1
  • Kosaku Fujiwara
    • 1
  1. 1.Department of Animal Pathology, Institute of Medical ScienceUniversity of TokyoMinato-ku, Tokyo 108Japan

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