Temporal Regulation of RNA Synthesis of Bovine Coronavirus
Part of the
Advances in Experimental Medicine and Biology
book series (AEMB, volume 218)
It has been shown with mouse hepatitis virus (MHV) and avian infectious bronchitis virus that all of the subgenomic mRNAs and genomic RNA are synthesized at the same rate throughout the viral replication cycle (Leibowitz et al., 1981; Stern and Kennedy, 1980). The viral genomic RNA gradually accumulates late in infection. However, no clear switching from transcription of subgenomic mRNAs to replication of genomic-sized RNA is seen. Thus, it is not known whether there is a temporal regulation of viral RNA synthesis in coronavirus-infected cells.
KeywordsMouse Hepatitis Virus Viral Replication Cycle Avian Infectious Bronchitis Virus Bovine CORONAVIRUS Subgenomic mRNAs
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Leibowitz, J.L., Wilhemsen, K.C. and Bond, C.W. The virus-specific intracellular RNA species of two murine coronaviruses: MHV-A59 and MHV-JHM. Virology 114: 29 (1981).CrossRefGoogle Scholar
Stern, D.F. and Kennedy, S.I.T. Coronavirus multiplication strategy, I. Identification of characterization of virus-specified RNA. J. Virology 34: 665 (1980).PubMedGoogle Scholar
© Plenum Press, New York 1987