Combined Use of Neuroleptic Drugs

  • Amos D. Korczyn


The therapeutic approach to schizophrenia has progressed considerably during the past years. The introduction of phenothiazines, butyrophenones and newer antipsychotic drugs has resulted in shorter hospitalizations and fewer relapses. There are now several dozens different antipsychotic drugs in clinical use. These belong to only a few families and, in fact, a chemical similarity exists between all of them (1). If this similarity is related to the mechanism of action of these drugs, then all should have the same clinical indications. On the whole, controlled trials aimed at finding “the right drug for the right patient” have not been very successful (2).


Antipsychotic Drug Spontaneous Activity Neuroleptic Drug Antipsychotic Activity Combine Medication 
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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • Amos D. Korczyn
    • 1
  1. 1.Department of Physiology and Pharmacology Sackler School of MedicineTel-Aviv UniversityIsrael

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