Mechanisms of Fluid Transport in Cartilaginous Tissues

  • Alice Maroudas


Cartilaginous tissues, such as articular cartilage and the intervertebral disc, consist of a network of collagen fibrils. These fibrils, capable of resisting tension but not compression, are embedded in an aqueous concentrated proteoglycan gel. The proteoglycans endow the matrix with a high osmotic pressure and a low hydraulic permeability, and hence constitute the compression-resisting component of these tissues.


Articular Cartilage Osmotic Pressure Intervertebral Disc Fluid Transport Collagen Network 
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  • Alice Maroudas

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