Pulmonary Tuberculosis

  • Milton D. Rossman
  • Robert L. Mayock
Part of the Clinical Topics in Infectious Disease book series (CLIN.TOP.INFECT)


The lung is the major portal of entry in the majority of cases of tuberculosis (7, 12). The first contact with the organism results in few or no clinical symptoms or signs. Ordinarily the tubercle bacillus sets up a localized infection in the periphery of the lung where it has been deposited by inhalation. Body defenses appear to have little effect on the organism until the time of development of tuberculin hypersensitivity (4–6 weeks). At this time, mild fever and malaise develop, and occasionally other hypersensitivity manifestations are noted.


Acquire Immune Deficiency Syndrome Pulmonary Tuberculosis Pleural Fluid Fiberoptic Bronchoscopy Bronchopleural Fistula 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Berger HW, Mejei E: Tuberculous pleurisy. Chest 1973;63:88–92.PubMedCrossRefGoogle Scholar
  2. 2.
    British Thoracic and Tuberculosis Association, Research Committee: Aspergilloma and residual tuberculous cavities — the results of a survey. Tubercle 1970;51:227–245.CrossRefGoogle Scholar
  3. 3.
    Comstock GW, Livesay VT, Woolpert SF: The prognosis of a positive tuberculin reaction in childhood and adolescence. Am J Epidemiol 1974;99:131.PubMedGoogle Scholar
  4. 4.
    Danek SJ, Bower JS: Diagnosis of pulmonary tuberculosis by flexible fiberoptic bronchoscopy. Am Rev Respir Dis 1979;119:677.PubMedGoogle Scholar
  5. 5.
    Fraser RG, Pare JAP: Diagnosis of Diseases of the Chest. Philadelphia, WB Saunders, 1977, pp 731–764.Google Scholar
  6. 6.
    Garibaldi RA, Drusin RE, Ferebee SH, et al: Isoniazid-associated hepatitis. Report of an outbreak. Am Rev Respir Dis 1972;106:357.PubMedGoogle Scholar
  7. 7.
    Glassroth J, Robbins AG, Snider DE: Tuberculosis in the 1980’s. N Engl J Med 1980;302:1441–1450.PubMedCrossRefGoogle Scholar
  8. 8.
    Holden M, Dubin MR, Diamond PH: Frequency of negative intermediate-strength tuberculin sensitivity in patients with active tuberculosis. N Engl J Med 1971;285:1560.CrossRefGoogle Scholar
  9. 9.
    Light RW, MacGregor MI, Luchsinger PC, et al: Pleural Effusions. The diagnostic separation of transudates and exudates. Ann Intern Med 1972;77: 507–555.PubMedCrossRefGoogle Scholar
  10. 10.
    MacGregor RR: A year’s experience with tuberculosis in a private urban teaching hospital in the postsanatorium era. Am J Med 1975;58:221.PubMedCrossRefGoogle Scholar
  11. 11.
    Mayock RL, Goldberg M: Metabolic considerations in disease of the respiratory system, in Duncan GG (ed): Diseases of Metabolism. Philadelphia, WB Saunders, 1964, pp 1395–1402.Google Scholar
  12. 12.
    Mayock RL, MacGregor RR: Diagnosis, prevention and early therapy of tuberculosis. Disease a Month May 1976;22:1–60.PubMedCrossRefGoogle Scholar
  13. 13.
    Pitchenik AE, Cole C, Russell BW, et al: Tuberculosis, atypical mycobacteriosis, and the acquired immunodeficiency syndrome among Haitian and non- Haitian patients in South Florida. Ann Intern Med 1984;101:641–645.PubMedCrossRefGoogle Scholar
  14. 14.
    Pitchenik AE, Rubinson HA: The radiographic appearance of tuberculosis in patients with the acquired immune deficiency syndrome (AIDS) and pre-AIDS. Am Rev Respir Dis 1985;131:393–396.PubMedGoogle Scholar
  15. 15.
    Poppius H, Thomander K: Segmentary distribution of cavities. A radiologic study of 500 consecutive cases of cavernous pulmonary tuberculosis. Ann Med Intern Fenn 1957;46:113.PubMedGoogle Scholar
  16. 16.
    Scerbo J, Keltz H, Stone DJ: A prospective study of closed pleural biopsies. JAMA 1971;218:377.PubMedCrossRefGoogle Scholar
  17. 17.
    Sunderam G, McDonald RJ, Maniatis T, et al: Tuberculosis as a manifestation of the acquired immunodeficiency syndrome (AIDS). JAMA 1986;256: 357–361.CrossRefGoogle Scholar
  18. 18.
    Wallace JM, Deutsch AL, Harrell JH, et al: Bronchoscopy and transbronchial biopsy in evaluation of patients with suspected active tuberculosis. Am J Med 1981;70:1189.PubMedCrossRefGoogle Scholar
  19. 19.
    Weber AL, Bird KT, Janower WL: Primary tuberculosis in childhood with particular emphasis on changes affecting the tracheobronchial tree. Am J Roentgenol 1968;103:123.CrossRefGoogle Scholar
  20. 20.
    Yam LT: Diagnostic significance of lymphocytes in pleural effusions. Am Rev Respir Dis 1972; 105:458–460.Google Scholar

Copyright information

© Springer-Verlag New York Inc. 1988

Authors and Affiliations

  • Milton D. Rossman
  • Robert L. Mayock

There are no affiliations available

Personalised recommendations