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Structural Characterization of IBV Glycoproteins

  • David Cavanagh
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 173)

Abstract

Avian infectious bronchitis virus (IBV) causes economically important disease in chickens, affecting both respiratory and non-respiratory tissues. Like other coronaviruses IBV virions contain three virus-coded protein structures, the spike (S; surface projection, peplomer), nucleocapsid (N) and matrix (M) proteins1. The polypeptides of M and N proteins have been identified. The M protein comprises a polypeptide of mol. wt. 23 000 (23K) which is glycosylated to different extents, the major glycopolypeptide being about 30K2,3,4. A polypeptide of about 50K forms the N protein5. However, although many papers have been published on the composition of IBV, there has been a distinct lack of agreement on the number and mol. wt. of the polypeptides which form the spikes (for references see1,6.

Keywords

Sucrose Gradient Disulphide Bond Infectious Bronchitis Virus Semliki Forest Virus High Mannose 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • David Cavanagh
    • 1
  1. 1.Houghton Poultry Research StationHoughton, HuntingdonUK

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