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Assembly of 229E Virions in Human Embryonic Lung Fibroblasts and Effects of Inhibition of Glycosylation and Glycoprotein Transport on this Process

  • M. C. Kemp
  • A. Harrison
  • J. C. Hierholzer
  • J. S. Burks
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 173)

Abstract

Assembly of virions in 229E infected cells were studied along with the effect(s) of an inhibitor of glycosylation (tunicamycin) and an inhibitor of glycoprotein transport (monensin) on this process. The results of these studies are summarized herein.

Keywords

Post Infection Double Membrane Veteran Administration Medical Human Embryonic Lung Perinuclear Space 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    M.C. Kemp, A. Harrison, J.C. Hierholzer, and J.S. Burks, Characterization of Viral Proteins Synthesized in 229E Infected Cells and Effect(s) of Inhibition of Glycosylation and Glycoprotein Transport (See these proceedings).Google Scholar
  2. 2.
    M.C. Kemp, A. Harrison, J.C. Hierholzer, and J.S. Burks, Electron Lucent Structures Induced by Coronaviruses (See these proceedings).Google Scholar
  3. 3.
    L.S. Ohiro, J.H. Schieble, and E.H. Lennette, Electron Microscopic Studies of Coronavirus, J. gen. Virol 12:161(1971).CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • M. C. Kemp
    • 1
    • 2
    • 3
  • A. Harrison
    • 4
  • J. C. Hierholzer
    • 4
  • J. S. Burks
    • 1
    • 2
    • 3
  1. 1.Center for Neurological DiseasesRocky Mountian Multiple Sclerosis CenterUSA
  2. 2.Veterans Administration Medical CenterUSA
  3. 3.Division of Viral DiseasesUniversity of Colorado School of MedicineDenverUSA
  4. 4.Centers for Disease ControlAtlantaUSA

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