Function and Structure of the Immune System pp 479-483 | Cite as
Different Cellular Site for the Production of Murine Macrophage Migration Inhibitory Factor and Immune Interferon (Type 11)
Chapter
Abstract
Macrophage migration inhibitory factor (MIF) and interferon (IF) belong to the biological activities found in lymphocyte cultures upon stimulation with antigen or mitogen (1,2). Further, both mediators were found to appear simultaneously in the serum of mice which had been immunized with BCG (3,4). As they could not be separated on a molecular weight basis, it was concluded that both activities might be two different functions of the same molecule.
Keywords
Migration Inhibitory Factor Lymphocyte Culture Macrophage Migration Inhibitory Factor Bone Marrow Macrophage Cellular Site
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© Plenum Press, New York 1979