The Detection of Chemical Mutagens with Enteric Bacteria
Mutagens alter DNA. As the DNA of all organisms has the same double helical structure and the same four nucleotides, any organism may be used as an indicator system for mutagens. Bacteria have numerous advantages for the detection of mutagens, and we discuss these and describe various methods and strains. We also discuss the validity of the bacterial tests and their pertinence to human mutagenesis and carcinogenesis.
KeywordsPetri Plate Enteric Bacterium Nitrogen Mustard Chemical Mutagen Nitrate Reductase Gene
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