Current Problems in Fertility pp 187-190 | Cite as
Possible Mechanism of the Anti-Fertility Effect of Copper
Chapter
Abstract
Zipper et al.(1969) reported that a small copper (or zinc) loop placed in the lower portion of one of the uterine horns in rabbits produced a decrease in the number of implantation sites without producing a significant alteration in the control uterus. Silver, tin and magnesium were not effective. Zipper and co-workers (1970) utilized this observation to design a copper-containing intrauterine device for the prevention of fertility in the human female and reported that clinical effectiveness was related to the amount of copper present (Table 1).
Keywords
Metallic Copper Uterine Horn Carbonic Anhydrase Activity Fertility Index Small Copper
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Preview
Unable to display preview. Download preview PDF.
References
- Chang C.C., and Tatum H. J. : Contraception 1 (1970) 265.CrossRefGoogle Scholar
- Chang C.C., Tatum H.J., and Kincl F.A. : Fertil. and Steril. 21(1970) 274.Google Scholar
- Frieden E. In: Horizons in Biochemistry, Kasha M. and Pullman B., Eds., Academic Press, New York (1962).Google Scholar
- Prager R.: Fertil.and Steril. 20 (1969) 944.Google Scholar
- Van Reen R.: Arch. Biochem. Biophys. 46 (1953) 337.CrossRefGoogle Scholar
- Zipper J., Medel M. and Prager R.: Amer. J. Obstet. Gynec. 105(1969) 529.Google Scholar
- Zipper J., Tatum H.J., Medel M., Pastene L. and Rivera M.: Presented at the 15th Nobel Symposium on Control of Human Fertility, May 27–29, 1970, Stockholm.Google Scholar
Copyright information
© Plenum Press, New York 1971