Functional Sequelae of Diastolic Sarcoplasmic Reticulum Ca2+ Release in the Myocardium

  • Edward G. Lakatta
  • Maurizio C. Capogrossi
  • Arthur A. Kort
  • Michael D. Stern


Routine cardiac catherization and angiography in patients with cardiac disease have permitted the measurement of not only systolic function but also of ventricular filling pressure and volume. The advent of ultrasound and radionuclide techniques has rendered the assessment of diastolic function, i.e. filling rates and volumes, and systolic function still more common. While these technological developments have verified the notion of variable diastolic compliance and the coexistence of “abnormal diastolic” function with normal or abnormal systolic “function,” the nature of the former and its relation to the latter still remain obscure.


Sarcoplasmic Reticulum Delay Interval Spontaneous Action Potential Mammalian Cardiac Muscle Contractile Wave 
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Copyright information

© Martinus Nijhoff Publishing 1987

Authors and Affiliations

  • Edward G. Lakatta
  • Maurizio C. Capogrossi
  • Arthur A. Kort
  • Michael D. Stern

There are no affiliations available

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