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Sarcoplasmic Reticular Control of Cardiac Contraction and Relaxation

  • Arnold M. Katz

Abstract

Any analysis of cardiac relaxation requires an understanding of the role of the sarcoplasmic reticulum (SR) in removing activator Ca2+ from the cytosol at the end of systole. The precise relationship between Ca2+ uptake into this intracellular membrane system and the changes in muscle length and tension that occur during diastole remains incompletely understood, but it is generally accepted that relaxation begins when cytosolic Ca2+ is reduced by the calcium pump of the SR.

Keywords

Sarcoplasmic Reticulum Adenosine Triphosphatase Calcium Pump Allosteric Effect Sarcoplasmic Reticulum Membrane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Martinus Nijhoff Publishing 1987

Authors and Affiliations

  • Arnold M. Katz

There are no affiliations available

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