Influence of Pressure and Volume Overload on Diastolic Compliance
Traditionally, the passive diastolic properties of the intact ventricle are assessed from the diastolic portion of the pressure-volume or pressure-length relationship. Compliance of the ventricular chamber refers to the ratio of change in volume (dV) to a change in pressure (dP). The reversed ratio represents chamber stiffness (dP/dV). The relationship between P and V throughout diastole is curvilinear. It is popular to fit the P-V data to an exponential relation, although in many instances (and also in pressure and volume overload) the observed P-V coordinates may clearly deviate from a true exponential relationship. The slope of the pressure-volume relation is termed the constant of chamber stiffness and represents a nonnormalized quantity of diastolic stiffness.
KeywordsAortic Valve Aortic Stenosis Aortic Valve Replacement Aortic Valve Disease Myocardial Stiffness
Unable to display preview. Download preview PDF.
- 13.Hess OM, Ritter M, Schneider J, et al (1984). Diastolic function in aortic valve disese: Techniques of evaluation and pre-/postoperative changes. Herz 9: 288–296.Google Scholar