Brewing with genetically modified amylolytic yeast

  • John Hammond
Chapter

Abstract

Yeast has a long history of industrial use, having been employed for the production of bread and alcoholic beverages since prehistoric times (Rose and Harrison, 1987). In all these processes yeast produces ethanol, carbon dioxide and numerous flavour compounds.

Keywords

Yeast Strain Genetic Modification Brewing Yeast Glucoamylase Activity Beer Production 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. ACGM/HSE/DOE (1993) Guidelines for the risk assessment of operations involving the contained use of genetically modified micro-organisms. Note 7, ACGM Secretariat, London.Google Scholar
  2. Andrews, B. J. et al. (1985) The FLP recombinase of the 2u circle DNA of yeast: interaction with its target sequences. Cell, 40, 795–803.CrossRefGoogle Scholar
  3. Aschengreen, N. H. (1987) Enzyme technology. Proceedings of the European Brewery Convention Congress, Madrid, 221–231.Google Scholar
  4. Berghof, K. and Stahl, U. (1991) Improving the filterability of beer by the use of β-glucanase active brewers’ yeast. BioEngineering, 7, 27–32.Google Scholar
  5. Cantwell, B. A. and McConnell, D. J. (1983) Molecular cloning and expression of a Bacillus subtilis β-glucanase gene in Escherichia coli. Gene, 23, 211–219.CrossRefGoogle Scholar
  6. Department of Health (1991) Guidelines on the assessment of novel foods and processes. Report on Health and Social Subjects, 38, HMSO, London.Google Scholar
  7. Enari, T. M. et al. (1987) Glucanolytic brewer’s yeast. Proceedings of the European Brewery Convention Congress, Madrid, 529–536.Google Scholar
  8. Fujii, T. et al. (1994) Molecular cloning, sequence analysis, and expression of the yeast alcohol acetyltransferase gene. Applied and Environmental Microbiology, 60, 2786–2792.Google Scholar
  9. Goelling, D. and Stahl, U. (1988) Cloning and expression of an α-acetolactate decarboxylase gene from Streptococcus lactis subsp. diacetylactis in Escherichia coli. Applied and Environmental Microbiology, 54, 1889–1891.Google Scholar
  10. Goossens, E. et al. (1993) Decreased diacetyl production in lager brewing yeast by integration of the ILV5 gene. Proceedings of the European Brewery Convention Congress, Oslo, 251–258.Google Scholar
  11. Hammond, J. R. M. (1995) Genetically-modified brewing yeasts for the 21st century. Progress to date. Yeast, 11, 1613–1627.CrossRefGoogle Scholar
  12. Hammond, J. R. M. (1996) Yeast genetics, in Brewing Microbiology, 2nd edn. (F. G. Priest and I. Campbell, eds), Chapman & Hall, London.Google Scholar
  13. Hansen, J. and Kielland-Brandt, M.C. (1995) Genetic control of sulphite production in brewer’s yeast. Proceedings of the European Brewery Convention Congress, Brussels, 319–328.Google Scholar
  14. Henderson, R. C. A., Cox, B. S. and Tubb, R. S. (1985) The transformation of brewing yeasts with a plasmid containing the gene for copper resistance. Current Genetics, 9, 133–138.CrossRefGoogle Scholar
  15. Jackson, E. A., Ballance, G. M. and Thomsen, K. K. (1986) Construction of a yeast vector directing the synthesis and release of barley 1–3,1–4–β–glucanase. Carlsberg Research Communications, 51, 445–458.CrossRefGoogle Scholar
  16. Kielland-Brandt, M. C. et al. (1989) Yeast breeding. Proceedings of the European Brewery Convention Congress, Zurich, 37–47.Google Scholar
  17. Knowles, J. K. C. et al. (1985) Transfer of genes coding for fungal glucanases into yeast. Proceedings of the European Brewery Convention Congress, Helsinki, 251–258.Google Scholar
  18. Korch, C. et al. (1991) A mechanism for sulphite production in beer and how to increase sulphite levels by recombinant genetics. Proceedings of the European Brewery Convention Congress, Lisbon, 201–208.Google Scholar
  19. Lancashire, W. E. and Wilde, R. J. (1987) Secretion of foreign proteins by brewing yeasts. Proceedings of the European Brewery Convention Congress, Madrid, 513–520.Google Scholar
  20. Livingstone, D. M. (1977) Inheritance of the 2μm DNA plasmid from Saccharomyces. Genetics, 86, 73–84.Google Scholar
  21. Meaden, P. G. et al. (1985) A DEX gene conferring production of extracellular amyloglucosidase on yeast. Gene, 34, 325–334.CrossRefGoogle Scholar
  22. Mellor, J. et al. (1983) Efficient synthesis of enzymatically active calf chymosin in Saccharomyces cerevisiae. Gene, 24, 1–14.CrossRefGoogle Scholar
  23. Omura, F. et al. (1995) Reduction of hydrogen sulphide production in brewing yeast by constitutive expression of MET25 gene. Journal of the American Society of Brewing Chemists, 53, 58–62.Google Scholar
  24. Ono, K. et al. (1988) Various molecular species in glucoamylase from Aspergillus niger. Agricultural and Biological Chemistry, 52, 1689–1698.CrossRefGoogle Scholar
  25. Pasteur, L. (1879) Studies on Fermentation. Macmillan & Co., London.Google Scholar
  26. Pecquet, S. et al. (1991) Kinetics of Saccharomyces cerevisiae elimination from the intestines of human volunteers and effect of this yeast on resistance to microbial colonization of gnotobiotic mice. Applied and Environmental Microbiology, 57, 3049–3051.Google Scholar
  27. Pretorius, I. S. et al. (1986) Molecular cloning and characterisation of the STA2 glucoamylase gene of Saccharomyces diastaticus. Molecular and General Genetics, 203, 29–35.CrossRefGoogle Scholar
  28. Rose, A. H. and Harrison, J. S. (1987) Introduction, in The Yeasts, Vol. 1. Biology of Yeasts (A. H. Rose and J. S. Harrison, eds). Academic Press, London.Google Scholar
  29. Tada, S. et al. (1995) Pilot scale brewing with industrial yeasts which produce the α-acetolactate decarboxylase of Acetobacter aceti ssp. xylinum. Proceedings of the European Brewery Convention Congress, Brussels, 369–376.Google Scholar
  30. Tezuka, H. et al. (1992) Cloning of a gene suppressing hydrogen sulphide production by Saccharomyces cerevisiae and its expression in a brewing yeast. Journal of the American Society of Brewing Chemists, 50, 130–133.Google Scholar
  31. Vakeria, D. and Hinchliffe, E. (1989) Amylolytic brewing yeast: their commercial and legislative acceptability. Proceedings of the European Brewery Convention Congress, Zurich, 475–482.Google Scholar
  32. Yamano, S., Tanaka, J. and Inoue, T. (1994) Cloning and expression of the gene encoding α-acetolactate decarboxylase from Acetobacter aceti ssp. xylinum in brewer’s yeast. Journal of Biotechnology, 32, 165–171.CrossRefGoogle Scholar
  33. Yamashita, I., Suzuki, K. and Fukui, S. (1985a) Nucleotide sequence of the extracellular glucoamylase gene STA1 in the yeast Saccharomyces diastaticus. Journal of Bacteriology, 161, 567–573.Google Scholar
  34. Yamashita, I. et al. (1985b) Polymorphic extracellular glucoamylase genes and their evolutionary origin in the yeast Saccharomyces diastaticus. Journal of Bacteriology, 161, 574–582.Google Scholar
  35. Yocum, R. R. (1986) Genetic engineering of industrial yeasts. Proceedings of Bio Expo 86, 171–180.Google Scholar

Copyright information

© Springer Science+Business Media Dordrecht 1998

Authors and Affiliations

  • John Hammond

There are no affiliations available

Personalised recommendations