Kindling 5 pp 285-298 | Cite as

Kindling in Genetically Altered Mice

Implications for the Role of LTP in Kindling
  • Donald P. Cain
Chapter
Part of the Advances in Behavioral Biology book series (ABBI, volume 48)

Abstract

Kindling is a neuroplastic process that appears to involve the lasting alteration of synaptic function. This implies that kindling may require a neural growth process for some aspect of its establishment. The fact that inhibition of protein synthesis blocks kindling without affecting the epileptiform afterdischarge (AD) that normally leads to its development [8] is consistent with that suggestion, as are reports of kindling-induced neural alterations and sprouting at the ultrastructural level [17,18,51].

Keywords

Focal Adhesion Kinase Long Term Potentiation AMPA Receptor Long Term Depression Dentate Granule Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Donald P. Cain
    • 1
  1. 1.Department of Psychology and Graduate Program in NeuroscienceUniversity of Western OntarioLondonCanada

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