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The Role of Dendritic Cells in the Initiation of Host Resistance to Toxoplasma Gondii

  • Alan Sher
  • Sara Hieny
  • Hugues Charest
  • Tanya Scharton-Kersten
  • Carmen Collazo
  • Ronald N. Germain
  • Caetano Reis e Sousa
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 452)

Abstract

Intracellular bacteria and protozoa typically stimulate host responses dominated by Type 1 cytokine production and cell-mediated immune effector functions. While the probable role of these responses is to limit growth of the infecting pathogen, the basis of their preferential induction is poorly understood and poses a fundamental question in immunologic class selection(1).

Keywords

Dendritic Cell Cell Area Toxoplasma Gondii Monocytic Cell Line Class Selection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Alan Sher
    • 1
  • Sara Hieny
    • 1
  • Hugues Charest
    • 1
  • Tanya Scharton-Kersten
    • 1
  • Carmen Collazo
    • 1
  • Ronald N. Germain
    • 2
  • Caetano Reis e Sousa
    • 2
  1. 1.Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious DiseasesNational Institutes of HealthBethesdaUSA
  2. 2.Laboratory of Immunology, National Institute of Allergy and Infectious DiseasesNational Institutes of HealthBethesdaUSA

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