Immunity and Prenatal Alcohol Exposure

A Pilot Study in Human Adolescents
  • Dorothy R. Oleson
  • Ronald M. Magee
  • Robert M. Donahoe
  • Arthur Falek
  • Claire D. Coles
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 437)


Alcohol has been recognized as a teratogen for over 150 years.1 In 1968, a constellation of birth defects which would become known as the Fetal Alcohol Syndrome (FAS) was described in France,2 and confirmed shortly thereafter in the United States.3 An explosion of case reports ensued, and a number of clinical and animal investigations were initiated.4 A general consensus from these studies is that in uteroalcohol exposure produces a continuum of alcohol-related birth defects, also known as fetal alcohol effects (FAE), and that FAS represents the severe end of that spectrum. To date, only limited human studies have been conducted on the immune status of children with FAS,5-7 and none have been done on alcohol-exposed children without the full-blown syndrome. The present study is aimed at filling these gaps in knowledge.


Allergic Rhinitis Fetal Alcohol Syndrome Absolute Lymphocyte Count Absolute Count Prenatal Alcohol Exposure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Dorothy R. Oleson
    • 1
  • Ronald M. Magee
    • 1
  • Robert M. Donahoe
    • 1
  • Arthur Falek
    • 1
  • Claire D. Coles
    • 1
  1. 1.Department of Psychiatry and Behavioral SciencesEmory University School of MedicineAtlantaUSA

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