Abstract
We have investigated the presence of Cytomegalovirus (CMV) in 15 patients with IgA Nephropathy (IgAN), 10 patients with other forms of glomerulonephritis and 10 age-matched controls. CMV has been detected in the urinary cells and circulating white blood cells by two different techniques: a) indirect immunofluorescence using monoclonal antobodies b) DNA probe based assay. Moreover, IgG and IgM antiCMV has been detected in IgAN patients, in the “other glomerulonephritis” patients and controls without any significant difference. Our findings do not support the hypothesis that CMV is specifically related to IgAN or is involved in the pathogenesis of IgAN.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Gregory MC, Hammond ME, Brewer ED. Lancet; ii: 11–15, 1988
Heieren M, van der Woude FJ, Balfour HH. Proc Natl Acad Sci USA; 85: 1642–46, 1988
Waldo FB, Britt WJ, Tomana M, Julian BA, Mestecky J. Lancet; i: 129–131, 1989
Okamura M, Kanayama Y, Negoro N, Takeda T, Inoue T. Lancet; ii: 1265, 1989
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Springer Science+Business Media Dordrecht
About this chapter
Cite this chapter
Pecoraro, C., Carbonaro, L., Manese, M., Saravo, M.T. (1991). IgA Nephropathy and Cytomegalovirus. In: Andreucci, V.E., Dal Canton, A. (eds) New Therapeutic Strategies in Nephrology. Developments in Nephrology, vol 30. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3884-4_25
Download citation
DOI: https://doi.org/10.1007/978-1-4615-3884-4_25
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-6732-1
Online ISBN: 978-1-4615-3884-4
eBook Packages: Springer Book Archive