Abstract
It has been recently suggested that prolonged administration of Cyclosporine (CsA) may determine a reduction of plasma volume (PV), potentially responsible for the nephrotoxicity induced by the drug ([1]). Aim of the present work was to evaluate the effects of a longterm treatment with CsA on PV, ANF, and on renal dynamics.
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References
Devarajan P et al. Cyclosporine nephrotoxicity: blood volume, sodium conservation, and renal hemodynamics. Am J Physiol 256:F71–F78, 1989.
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Thomson SC et al. Functional effects on glomerular hemodynamics of short-term chronic cyclosporine in male rats. J Clin Inv 83:960–969, 1989.
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© 1991 Springer Science+Business Media Dordrecht
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Sabbatini, M., De Nicola, L., Sansone, G., Uccello, F., Veniero, P., Fuiano, G. (1991). Modifications of Plasma Volume and ANF During Long-Term Administration of Cyclosporie. In: Andreucci, V.E., Dal Canton, A. (eds) New Therapeutic Strategies in Nephrology. Developments in Nephrology, vol 30. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3884-4_146
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DOI: https://doi.org/10.1007/978-1-4615-3884-4_146
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