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High Dose Intravenous Human IgG in the Treatment of Idiopathic Membranous Nephropathy: Preliminary Report of a Multicentric Trial

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New Therapeutic Strategies in Nephrology

Abstract

Twenty six adult patients were treated with high dose intravenous immuneglobulin (Endobulin-Immuno) for idiopathic membranous nephropathy and nephrotic syndrome.Pulse doses of 0.4 g/Kg b. wt. for 3 consecutive days were given and repeated twice after 3 weeks. Afterwards, one pulse dose every 3 weeks has been administered for a 12 months period. At the end of the study, 11 patients had a complete remission (daily proteinuria <0.2 g), 8 patients had a partial remission (daily proteinuria ≤3.5 g. mean 2.27±0.6 g).On the whole, 19 responders (73%) and 7 non-responders (27%).

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References

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© 1991 Springer Science+Business Media Dordrecht

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Palla, R. et al. (1991). High Dose Intravenous Human IgG in the Treatment of Idiopathic Membranous Nephropathy: Preliminary Report of a Multicentric Trial. In: Andreucci, V.E., Dal Canton, A. (eds) New Therapeutic Strategies in Nephrology. Developments in Nephrology, vol 30. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3884-4_13

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  • DOI: https://doi.org/10.1007/978-1-4615-3884-4_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6732-1

  • Online ISBN: 978-1-4615-3884-4

  • eBook Packages: Springer Book Archive

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