Abstract
Twenty six adult patients were treated with high dose intravenous immuneglobulin (Endobulin-Immuno) for idiopathic membranous nephropathy and nephrotic syndrome.Pulse doses of 0.4 g/Kg b. wt. for 3 consecutive days were given and repeated twice after 3 weeks. Afterwards, one pulse dose every 3 weeks has been administered for a 12 months period. At the end of the study, 11 patients had a complete remission (daily proteinuria <0.2 g), 8 patients had a partial remission (daily proteinuria ≤3.5 g. mean 2.27±0.6 g).On the whole, 19 responders (73%) and 7 non-responders (27%).
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Imbach, P., Barandun, S., d’Apuzzo, V., Baumgartner, C., Hirt, A., Morell, A., Rosi, E., Schoni, M., Wagner, H. P. Lancet i, 1228–1231, 1981.
Ponticelli, C., Zucchelli, P., Passerini, P., Cagnoli, L., Cesana, B., Pozzi, C., Pasquali, S., Imbasciati, E., GRassi, C., Redaelli, B., Sasdelli M., Locatelli, F. New Eng J Med 320, 8–13, 1989.
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© 1991 Springer Science+Business Media Dordrecht
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Palla, R. et al. (1991). High Dose Intravenous Human IgG in the Treatment of Idiopathic Membranous Nephropathy: Preliminary Report of a Multicentric Trial. In: Andreucci, V.E., Dal Canton, A. (eds) New Therapeutic Strategies in Nephrology. Developments in Nephrology, vol 30. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3884-4_13
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DOI: https://doi.org/10.1007/978-1-4615-3884-4_13
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