Antioxidant and Hepatoprotective Properties of IdB 1016, A New Flavanolignan Complex

  • R. Carini
  • A. Comoglio
  • H. Basaga
  • E. Albano
  • G. Poli
Part of the Developments in Oncology book series (DION, volume 71)

Abstract

The new form of silybin, IdB 1016, displays good antioxidant and free radical scavenging properties in isolated rat hepatocytes treated with CBrCl3, allyl alcohol and cumene hydroperoxide following both in vivo and in vivo administration of this flavanolignan.

Keywords

Allyl Alcohol Cumene Hydroperoxide Good Antioxidant Free Radical Scavenge Property Human Liver Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Ferenci, P., Dragosiscs, B., Dittrich, H., Frank, H., Benda, L, Lochs, H., Meryn, S., Base, W. and Shneider, B. J. Hepatol. 9, 105–113, 1989.PubMedCrossRefGoogle Scholar
  2. 2.
    Barzaghi, N., Perucca, G., Pifferi, G. European J. Clin. Pharmacol., 36, A110, 1989.Google Scholar
  3. 3.
    Comoglio, A., Leonarduzzi, G., Carini, R., Busolin, D., Basaga, H., Albano, E., Tomasi, A., Poli, G., Morazzoni, P. and Magistretti, M.J. Free Rad. Res. Comms., 11, 109–115, 1990.CrossRefGoogle Scholar
  4. 4.
    Poli, G., Gravela, E., Albano, E. and Dianzani, M.U., Exp. Mol. Pathol. 30, 116–127, 1979.PubMedCrossRefGoogle Scholar
  5. 5.
    Silva, M.J. and O’Brien, P.J. Arch. Biochem. Biophys., 275, 551–558, 1989.PubMedCrossRefGoogle Scholar
  6. 6.
    Poli, G., Albano, E. and Dianzani, M. U. Chem. Phys. Lip., 45, 117–142, 1987.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • R. Carini
    • 1
  • A. Comoglio
    • 1
  • H. Basaga
    • 2
  • E. Albano
    • 1
  • G. Poli
    • 2
  1. 1.Department of Experimental Medicine and OncologyUniversity of Torino and CNR Center for Immunogenetics and Experimental OncologyTorinoItaly
  2. 2.Department of Science EducationMiddle East Technical UniversityAnkaraTurkey

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