Modern Concepts in Gastroenterology pp 157-166 | Cite as
Management of the Irritable Bowel
Abstract
The irritable bowel syndrome affects 15-20% of people.1,2 Fortunately, most sufferers do not seek medical attention. Those who do constitute an important health problem and make up 30-50% of referrals to Western gastroen-terologists.3 Most patients are female, and there is an association with personality or psychiatric disturbance, but amongst noncomplainers the sexes are equally represented and psychosocial backgrounds are similar among nonsufferers.4,5 Threatening life events often precede the patient’s visit to a doctor.6,7 The IBS is a benign condition with no organic consequences other than those resulting from injudicious tests or treatments. It usually begins in youth and continues or recurs throughout life.8-10 Thus, any management strategy must take into account the patient’s psychosocial history, the benign but lifelong nature of the symptoms, and the lack of any generally accepted pathophysiologic conception of how the symptoms are generated.
Keywords
Irritable Bowel Syndrome Lower Esophageal Sphincter Positive Diagnosis Supportive Psychotherapy Irritable Colon SyndromePreview
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References
- 1.Thompson WG, Heaton K. Functional bowel disorders in apparently healthy people. Gastroenterology 1980; 79: 283–288.PubMedGoogle Scholar
- 2.Drossman DA, Sandler RS, McKee DE, et al. Bowel dysfunction among subjects not seeking health care. Gastroenterology 1982; 83: 529–534.PubMedGoogle Scholar
- 3.Thompson WG. Irritable bowel syndrome: prevalence, prognosis and consequences. Can Med Assoc J 1986; 134: 110–113.Google Scholar
- 4.Drossman DA, McKee DC, Sandler RS, et al. Psychosocial factors in the irritable bowel syndrome: a multivariate study of patients and non-patients with IBS. Gastroenterology 1988; 95: 701–708.PubMedGoogle Scholar
- 5.Whitehead WE, Bosmajian L, Zonderman A, et al. Psychological distress associated with irritable bowel syndrome: comparison of community and medical clinic samples. Gastroenterology 1988; 95: 709–714.PubMedGoogle Scholar
- 6.Creed F. Life events and appendectomy. Lancet 1981; 1: 1381–1385.PubMedCrossRefGoogle Scholar
- 7.Craig TKJ, Brown GW. Goal frustration and life events in the etiology of painful gastrointestinal disorder. J Psychosom Res 1984; 28: 411–421.PubMedCrossRefGoogle Scholar
- 8.Harvey RF, Mauad AC, Brown AM. Prognosis in the irritable bowel syndrome: a 5 year prospective study. Lancet 1987; 1: 963–965.PubMedCrossRefGoogle Scholar
- 9.Svendsen JH, Munck LK, Andersen JR. Irritable bowel syndrome—prognosis and diagnostic safety. Scand J Gastroenterol 1985; 20: 415–418.PubMedCrossRefGoogle Scholar
- 10.Holmes IM, Salter RH. Irritable bowel syndrome—a safe diagnosis. Br Med J 1982; 285: 1533–1534.CrossRefGoogle Scholar
- 11.Thompson WG, Dotevall G, Drossman DA, et al. Irritable bowel syndrome: guidelines for the diagnosis. Gastroenterol Int 1989; 2: 92–95.Google Scholar
- 12.Manning AP, Thompson WG, Heaton KW, Morris AF. Towards positive diagnosis of the irritable bowel. Br Med J 1978; 2: 653–654.PubMedCrossRefGoogle Scholar
- 13.Kruis W, Thieme CH, Weinzier M, et al. A diagnostic score for the irritable bowel syndrome, its value in exclusion of organic disease. Gastroenterology 1984; 87: 1–7.PubMedGoogle Scholar
- 14.Thompson WG. Gut Reactions. New York: Plenum, 1989, pp. 181–211 (chap. 13).Google Scholar
- 15.Thompson WG. The irritable bowel. Gut 1984; 25: 305–320.PubMedCrossRefGoogle Scholar
- 16.Thompson WG. A strategy for management of the irritable bowel. Am J Gastroenterol 1986; 81: 95–100.PubMedGoogle Scholar
- 17.Drossman DA. The physician and the patient. In: Gastrointestinal Disease (Sleisenger MH, Fortran JS, eds). Philadelphia: W. B. Saunders, 1983, chap. 1.Google Scholar
- 18.Creed F, Guthrie E. Psychological factors and the irritable bowel syndrome. Gut 1987; 28: 1307–1318.PubMedCrossRefGoogle Scholar
- 19.Swedlund J, Sjodin I, Ottosson JO, et al. Controlled study of psychotherapy in irritable bowel syndrome. Lancet 1983; 2: 589–591.CrossRefGoogle Scholar
- 20.Guthrie E, Creed F, Dawson D, Tomenson B. A controlled trial of psychological treatment for the irritable bowel syndrome. Gastroenterology 1991; 100: 450–457.PubMedGoogle Scholar
- 21.Heaton KW. Role of dietary fibre in irritable bowel syndrome. In: Irritable Bowel Syndrome (Read NW, ed). London: Grunne and Stratton, 1985, pp. 203–222 (chap. 18).Google Scholar
- 22.Feldman W, McGrath P, Hodgson C, et al. The use of dietary fibre in the management of simple, childhood, idiopathic recurrent abdominal pain. Am J Dis Child 1985; 139: 1216–1218.PubMedGoogle Scholar
- 23.Thompson WG, Patel DG, Tao H, Nair RC. Does uncomplicated diverticular disease produce symptoms? Dig Dis Sci 1982; 27: 605–608.PubMedCrossRefGoogle Scholar
- 24.Prior A, Whorwell PJ. Double blind study of Isbagula in irritable bowel syndrome. Gut 1987; 28: 1510–1513.PubMedCrossRefGoogle Scholar
- 25.Thompson WG. Gut Reactions. New York: Plenum, 1989, pp. 15–29 (chap. 2).Google Scholar
- 26.Brody H. The lie that heals: the ethics of giving placebos. Ann Intern Med 1982; 97: 112–118.PubMedGoogle Scholar
- 27.Klein KB. Controlled treatment trials in the irritable bowel syndrome: a critique. Gastroenterology 1988; 95: 232–241.PubMedGoogle Scholar
- 28.Cann PA, Read NW, Holdsworth DP, et al. Role of loperamide in management of irritable bowel syndrome. Dig Dis Sci 1984; 29: 239–242.PubMedCrossRefGoogle Scholar
- 29.Read MW, Read NW, Barber DC, et al. Effects of loperamide on anal sphincter function in patients complaining of chronic diarrhea with fecal incontinence and urgency. Dig Dis Sci 1982; 27: 807–813.PubMedCrossRefGoogle Scholar
- 30.Thaysen EH, Pedersen L. Idiopathic bile salt catharsis. Gut 1976; 17: 965–970.PubMedCrossRefGoogle Scholar
- 31.Goulston K. Drug usage in the irritable colon syndrome. Med J Aust 1972; 1: 1126–1131.PubMedGoogle Scholar
- 32.Ivey KJ. Are anticholinergics of use in the irritable colon syndrome? Gastroenterology 1975; 68: 1300–1307.PubMedGoogle Scholar
- 33.Centonze V, Imbimbo BP, Campanozzi F, et al. Oral cimetropium bromide, a new muscarinic drug, for long-term treatment of irritable bowel syndrome. Am J Gastroenterol 1988; 83: 1262–1266.PubMedGoogle Scholar
- 34.Page JG, Dirnberger MS. Treatment of the irritable colon syndrome with bentyl (dicyclomine hydrochloride). J Clin Gastroenterol 1988; 3: 153–156.CrossRefGoogle Scholar
- 35.Sullivan MA, Cohen SJ, Snape WJ. Colonic myoelectric activity in irritable bowel syndrome: effect of eating and anticholinergics. N Engl J Med 1978; 298: 878–883.PubMedCrossRefGoogle Scholar
- 36.Myren J, Lovland B, Larssen S, Larsen S. Psychopharmacologic drugs in the treatment of the irritable bowel syndrome: a double blind study of effect of trimipramine. Ann Gastroenterol Hepatol 1984; 20: 117–123.Google Scholar
- 37.Narducci F, Bassotti G, Gaburri M, et al. Nifedipine reduces the colonic motor response to eating in patients with the irritable colon syndrome. Am J Gastroenterol 1985; 80: 317–319.PubMedGoogle Scholar
- 38.Powell-Tuck J, MacRae KD, Healy MJR, et al. A defence of the small clinical trial: evaluation of three gastroenterological studies. Br Med J 1986; 292: 599–602.CrossRefGoogle Scholar
- 39.Perez-Mateo M, Sillero C, Cuesta A, et al. Diltiazem in the treatment of the irritable bowel syndrome. Int J Clin Pharm Res 1986; 6: 425–427.Google Scholar
- 40.Rees WDW, Evans BK, Rhodes J. Treating irritable bowel syndrome with peppermint oil. Br J Med 1979; 2: 835–836.CrossRefGoogle Scholar
- 41.Nash P, Gould SR, Barnardo DE. Peppermint oil does not relieve the pain of irritable bowel syndrome. Br J Clin Pract 1986; 40: 292–293.PubMedGoogle Scholar
- 42.Sigmund CJ, McNally EF. The action of a carminative on the lower esophageal sphincter. Gastroenterology 1969; 56: 13–18.PubMedGoogle Scholar
- 43.Smart HL, Mayberry JF, Atkinson M. Alternative medicine and remedies in patients with irritable bowel syndrome. Gut 1986; 27: 826–828.PubMedCrossRefGoogle Scholar
- 44.Jones VA, McLaughlin P, Shorthouse M, et al. Food intolerance: a major factor in the pathogenesis of the irritable bowel syndrome. Lancet 1972; 2: 1115–1117.Google Scholar
- 45.Bentley SJ, Pearson DJ. Food hypersensitivity in irritable bowel syndrome. Lancet 1983; 2: 295–297.PubMedCrossRefGoogle Scholar
- 46.Whorwell PJ, Prior A, Faragher EB. Controlled trial of hypotherapy in the treatment of severe refractory irritable bowel syndrome. Lancet 1985; 2: 1232.Google Scholar