Blastomycosis pp 165-188 | Cite as

Clinical Aspects of Blastomycosis

  • William A. Causey
  • Guy D. Campbell
Chapter
Part of the Current Topics in Infectious Disease book series (CTID)

Abstract

What is known of the spectrum of disease caused by Blastomyces dermatitidis comes from the study of published reports of sporadic cases, reviews of clinical experience of individual medical centers in endemic areas, from cooperative studies of investigators combining their experiences, and from studies of a few point-source outbreaks of blastomycosis. To this, the authors add their personal experience in diagnosis and treatment of patients with this disease.

Keywords

Acquire Immune Deficiency Syndrome Acquire Immune Deficiency Syndrome Patient Extrapulmonary Manifestation Positive Sputum Culture Adrenal Involvement 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. 1.
    Schwarz J, Baum GL: Blastomycosis. Am J Clin Pathol 21:999–1029, 1951PubMedGoogle Scholar
  2. 2.
    Abernathy RS: Clinical manifestations of pulmonary blastomycosis. Ann Intern Med 51:707–727,1959PubMedGoogle Scholar
  3. 3.
    Busey JF: Blastomycosis. 1. Review of 198 collected cases in Veterans Administration hospitals. Am Rev Respir Dis 89:659–672, 1964Google Scholar
  4. 4.
    Witorsch P, Utz JP: North American blastomycosis: A study of 40 patients. Medicine 47:169–200, 1968PubMedCrossRefGoogle Scholar
  5. 5.
    Lin AC, Morris K, Hendricks K, et al: Epidemiologic and clinical study of endemic blastomycosis in MS (Abstract 270). Proceedings of the 29th Interscience Conference on Antimicrobial Agents and Chemotherapy, Houston, September 17–20, 1989Google Scholar
  6. 6.
    Baum GL, Lerner PL: Primary pulmonary blastomycosis: A laboratory-acquired infection. Ann Intern Med 73:263–265, 1970PubMedGoogle Scholar
  7. 7.
    Smith JG Jr, Harris JS, Conant NF, et al: An epidemic of North American blastomycosis. JAMA 158:641–646, 1955CrossRefGoogle Scholar
  8. 8.
    Tosh FE, Hammerman KJ, Weeks RJ, et al: A common source epidemic of North American blastomycosis. Am Rev Respir Dis 109:525–529, 1974PubMedGoogle Scholar
  9. 9.
    Kitchen MS, Reiber CD, Eastin GB: An urban epidemic of North American blastomycosis. Am Rev Respir Dis 115:1063–1066, 1977PubMedGoogle Scholar
  10. 10.
    Blastomycosis—North Carolina. MMWR 25:205–206, 1976Google Scholar
  11. 11.
    Cockerill FR III, Roberts GD, Rosenblatt JE, et al: Epidemic of pulmonary blastomycosis (Namekagon fever) in Wisconsin canoeists. Chest 86:688–692, 1984PubMedCrossRefGoogle Scholar
  12. 12.
    Armstrong CW, Jenkins SR, Kaufman L, et al: Common-source outbreak of blastomycosis in hunters and their dogs. J Infect Dis 155:568–570, 1987PubMedCrossRefGoogle Scholar
  13. 13.
    Klein BS, Vergeront JM, Weeks RJ, et al: Isolation of Blastomyces dermatitidis in soil associated with a large outbreak of blastomycosis in Wisconsin. N Engl J Med 314:529–534, 1986PubMedCrossRefGoogle Scholar
  14. 14.
    Klein BS, Vergeront JM, DiSalvo AF: Two outbreaks of blastomycosis along rivers in Wisconsin. Isolation of Blastomyces dermatitidis from riverbank soil and evidence of its transmission along waterways. Am Rev Respir Dis 136:1333–1338, 1987PubMedCrossRefGoogle Scholar
  15. 15.
    Rabinowitz JG, Busch J, Buttram WR: Pulmonary manifestations of blastomycosis. Radiological support of a new concept. Radiology 120:25–32, 1976PubMedGoogle Scholar
  16. 16.
    Cush R, Light RW, George RB: Clinical and roentgenographic manifestations of acute and chronic blastomycosis. Chest 69:345–349, 1976PubMedCrossRefGoogle Scholar
  17. 17.
    Kinasewitz GT, Penn RL, George RB: The spectrum and significance of pleural disease in blastomycosis. Chest 86:580–584, 1984PubMedCrossRefGoogle Scholar
  18. 18.
    Arora NS, Oblinger MJ, Feldman PS: Chronic pleural blastomycosis with hyperprolactinemia, galactorrhea, and amenorrhea.Am Rev Respir Dis120:451–455, 1979PubMedGoogle Scholar
  19. 19.
    Nelson O, Light RW: Granulomatous pleuritis secondary to blastomycosis. Chest 71:433–434, 1977PubMedCrossRefGoogle Scholar
  20. 20.
    Edson RS, Keys TF: Treatment of primary pulmonary blastomycosis. Results of long-term follow-up. Mayo Clin Proc 56:683–685, 1981PubMedGoogle Scholar
  21. 21.
    Griffith JE, Campbell GD: Acute miliary blastomycosis presenting as fulminating respiratory failure. Chest 75:630–632, 1979PubMedCrossRefGoogle Scholar
  22. 22.
    Shaw GB, Campbell GD, Busey JF: Miliary blastomycosis. Am Rev Respir Dis 113:81,1976Google Scholar
  23. 23.
    George RB: Pulmonary mycoses. New concepts and new therapy. Postgrad Med 84:185–194, 1988Google Scholar
  24. 24.
    Stelling CB, Woodring JH, Rehm SR, et al: Miliary pulmonary blastomycosis. Radiology 150:7–13, 1984PubMedGoogle Scholar
  25. 25.
    Campbell G, Brunson JG: Clinicopathological conference: Miliary disease of the lung. J Miss State Med Assoc 14:196–201, 1973PubMedGoogle Scholar
  26. 26.
    Busey JF: North American blastomycosis. Am Fam Physician/GP 30:88–95, 1964Google Scholar
  27. 27.
    Larsh HW, Schwarz J: Accidental inoculation blastomycosis. Cutis 19:334–337, 1977PubMedGoogle Scholar
  28. 28.
    Scott MJ: Cutaneous blastomycosis. Report of case following dog bite. Northwest Med 54:255–257, 1955PubMedGoogle Scholar
  29. 29.
    Jaspers RH: Transmission of blastomyces from animals to man. J Am Vet Med Assoc 164:8, 1974PubMedGoogle Scholar
  30. 30.
    Gnann JW Jr, Bressler GS, Bodet CA III, et al: Human blastomycosis after a dog bite. Ann Intern Med 98:48–49, 1983PubMedGoogle Scholar
  31. 31.
    Farber ER, Leahy MS, Meadows TR: Endometrial blastomycosis acquired by sexual contact. Obstet Gynecol 32:195–199, 1968PubMedGoogle Scholar
  32. 32.
    Dyer ML, Young TL, Kattine AA, et al: Blastomycosis in a Papanicolaou smear. Report of a case with possible venereal transmission. Acta Cytol 27:285–287, 1983PubMedGoogle Scholar
  33. 33.
    Sanders LL: Blastomycosis arthritis. Arthritis Rheum 10:91–98, 1967PubMedCrossRefGoogle Scholar
  34. 34.
    Fountain FF Jr: Acute blastomycotic arthritis. Arch Intern Med 132:684–688, 1973PubMedCrossRefGoogle Scholar
  35. 35.
    George AL Jr, Hays JT, Graham BS: Blastomycosis presenting as monarticular arthritis. The role of synovial fluid cytology. Arthritis Rheum 28:516–521, 1985PubMedCrossRefGoogle Scholar
  36. 36.
    Chapman SW:Blastomyces dermatitidis,in Mandell GL, Douglas RG Jr, Bennett JE(eds): Principles and Practice of Infectious Diseases, ed 3.Edinburgh, Churchill Livingstone, 1990, p 1999Google Scholar
  37. 37.
    Malin JM Jr, Anderson EE, Weber CH: North American blastomycosis of the urogenital tract. J Urol 102:754–757, 1969PubMedGoogle Scholar
  38. 38.
    Schwarz J, Salfelder K: Blastomycosis. A review of 152 cases. Curr Top Patho165:165–200, 1977CrossRefGoogle Scholar
  39. 39.
    Hamblen EC, Baker RD, Martin DS: Blastomycosis of the female reproductive tract. With report of a case. Am J Obstet Gynecol 30:345–356, 1935Google Scholar
  40. 40.
    Murray JJ, Clark CA, Lands RH, et al: Reactivation blastomycosis presenting as a tubo-ovarian abscess. Obstet Gynecol 64:828–830, 1984PubMedGoogle Scholar
  41. 41.
    Faro S, Pastorek JG III, Collins J, et al: Severe uterine hemorrhage from blastomycosis of the endometrium. A case report. J Reprod Med 32:247–249, 1987PubMedGoogle Scholar
  42. 42.
    Ferguson GB: North American blastomycosis. A review of the literature and a report of two cases primary in the larynx. Laryngoscope 61:851–873, 1951Google Scholar
  43. 43.
    Payne J, Koopmann CF Jr: Laryngeal carcinoma—or is it laryngeal blastomycosis. Laryngoscope 94:608–611, 1984PubMedCrossRefGoogle Scholar
  44. 44.
    Dumich PS, Neel HB III: Blastomycosis of the larynx. Laryngoscope 93:1266–1270, 1983PubMedGoogle Scholar
  45. 45.
    Buechner HA, Clawson CM: Blastomycosis of the central nervous system. II. A report of nine cases from the Veterans Administration Cooperative Study. Am Rev Respir Dis 95:820–826, 1967PubMedGoogle Scholar
  46. 46.
    Gonyea EF: The spectrum of primary blastomycotic meningitis: A review of central nervous system blastomycosis. Ann Neurol 3:26–39, 1978PubMedCrossRefGoogle Scholar
  47. 47.
    Kravitz GR, Davies SF, Eckman MR, et al: Chronic blastomycotic meningitis. Am J Med 71:501–505, 1981PubMedCrossRefGoogle Scholar
  48. 48.
    Kaufman L: Mycoserology: Its vital role in diagnosing systemic mycotic infections. Jpn J Med Mycol 24:1–8, 1983CrossRefGoogle Scholar
  49. 49.
    Abernathy RS, Melby JC: Addison’s disease in North American blastomycosis. N Engl J Med 266:552–554, 1962PubMedCrossRefGoogle Scholar
  50. 50.
    Eberle DE, Evans RB, Johnson RH: Disseminated North American blastomycosis. Occurrence with clinical manifestations of adrenal insufficiency. JAMA 238:2629–2630, 1977PubMedCrossRefGoogle Scholar
  51. 51.
    Chandler PT: Addison’s disease secondary to North American blastomycosis. South Med J 70:863–864, 1977PubMedCrossRefGoogle Scholar
  52. 52.
    Martin DS, Smith DT: Blastomycosis (American blastomycosis, Gilchrist’s disease); a review of the literature. Am Rev Tuberc 39:275–304, 1939Google Scholar
  53. 53.
    Pond NE, Humphreys RJ: Blastomycosis with cardiac involvement and peripheral emboli-zation. Am Heart J 43:615–620, 1952PubMedCrossRefGoogle Scholar
  54. 54.
    Merchant RK, Louria DB, Geisler PH, et al: Fungal endocarditis: Review of the literature and report of three cases. Ann Intern Med 48:242–266, 1958PubMedGoogle Scholar
  55. 55.
    Cherniss EI, Waisbren BA: North American blastomycosis: A clinical study of 40 cases. Ann Intern Med 44:105–123, 1956PubMedGoogle Scholar
  56. 56.
    McKenzie R, Khakoo R: Blastomycosis of the esophagus presenting with gastrointestinal bleeding. Gastroenterology 88:1271–1273, 1985PubMedGoogle Scholar
  57. 57.
    Seymour EQ: Blastomycosis of the breast. AJR 139:822–823, 1982PubMedGoogle Scholar
  58. 58.
    Chapman SW, University of Mississippi School of Medicine, Jackson MS, Personal communication, 1990Google Scholar
  59. 59.
    Louis T III,Lockey MW: Blastomycosis of the middle ear cleft.South Med J67:1489–1491,1974PubMedCrossRefGoogle Scholar
  60. 60.
    Habte-Gabr E, Smith IM: North American blastomycosis in Iowa: Review of 34 cases. J Chronic Dis 26:585–594, 1973PubMedCrossRefGoogle Scholar
  61. 61.
    Duttera MJ Jr, Osterhout S: North American blastomycosis: A survey of 63 cases. South Med J 62:295–301, 1969PubMedGoogle Scholar
  62. 62.
    Kunkel WM Jr, Weed LA, McDonald JR, et al: North American blastomycosisGilchrist’s disease: A clinicopathologic study of ninety cases. Int Abstr Surg 99:1–25, 1954PubMedGoogle Scholar
  63. 63.
    Catanzaro A: Pulmonary mycosis in pregnant women. Chest Suppl 86:14S–18S, 1984PubMedGoogle Scholar
  64. 64.
    Watts EA, Gard PD Jr, Tuthill SW: First reported case of intrauterine transmission of blastomycosis. Pediatr Infect Dis 2:308–310, 1983PubMedCrossRefGoogle Scholar
  65. 65.
    Daniel L, Salit IE: Blastomycosis during pregnancy. Can Med Assoc J 131:759–761, 1984PubMedGoogle Scholar
  66. 66.
    Hager H, Welt SI, Cardasis JP, et al: Disseminated blastomycosis in a pregnant woman successfully treated with amphotericin-B. A case report. JReprod Med 33:485–488, 1988Google Scholar
  67. 67.
    Ismail MA, Lerner SA: Disseminated blastomycosis in a pregnant woman. Review of amphotericin B usage during pregnancy. Am Rev Respir Dis 126:350–353, 1982PubMedGoogle Scholar
  68. 68.
    Salfelder K, Mendelovici M, Schwarz J: Multiple deep fungus infections: Personal observations and a critical review of the world literature. Curr Top Pathol 57:123–177, 1973PubMedGoogle Scholar
  69. 69.
    Davidson W, Sarosi GA: Disseminated blastomycosis and cocciciodomycosis in the same patient. Am Rev Respir Dis 124:179, 1981PubMedGoogle Scholar
  70. 70.
    Dismukes WE, Stamm AM, Graybill JR, et al: Treatment of systemic mycoses with ketoconazole: Emphasis on toxicity and clinical response in 52 patients. Ann Intern Med 98:1320, 1983Google Scholar
  71. 71.
    Pechan WB, Novick AC, Lalli A, et al: Pulmonary nodules in a renal transplant recipient. J Urol 124:111–114, 1980PubMedGoogle Scholar
  72. 72.
    Steele RW, Abernathy RS: Systemic blastomycosis in children. Pediatr Infect Dis 2:304–310, 1983PubMedCrossRefGoogle Scholar
  73. 73.
    Powell DA, Schuit KE: Acute pulmonary blastomycosis in children: Clinical course and follow-up. Pediatrics 63:736–740, 1979PubMedGoogle Scholar
  74. 74.
    Recht LD, Davies SF, Eckman MR, et al: Blastomycosis in immunosuppressed patients. Am Rev Respir Dis 125:359–362, 1982PubMedGoogle Scholar
  75. 75.
    ButkaBJ, Bennett SR, Johnson AC: Disseminated inoculation blastomycosis in a renal transplant recipient. Am Rev Respir Dis 130:1180–1183, 1984PubMedGoogle Scholar
  76. 76.
    Winston DJ, Gale RP, Meyer DV, et al: Infectious complications of human bone marrow transplantation. Medicine 58:1–31, 1979PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • William A. Causey
  • Guy D. Campbell

There are no affiliations available

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