Radiotherapy of melanoma

  • Michael J. Dougherty
  • Morton M. Kligerman
Part of the Cancer Treatment and Research book series (CTAR, volume 65)

Abstract

This chapter discusses the radiobiology of melanoma as well as the clinical application of radiotherapy to patients with primary and metastatic disease. The treatment of ocular melanomas is addressed in Chapter 7.

Keywords

Brain Metastasis Metastatic Malignant Melanoma Melanoma Cell Line Cerebral Metastasis Solitary Metastasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Rofstad EK. 1986. Radiation biology of malignant melanoma. Acta Radiol 25:1.CrossRefGoogle Scholar
  2. 2.
    Barranco SC, Romsdahl MM, Humphrey RM. 1971. The radiation response of human melanoma cell grown in vitro. Cancer Res 31:830.PubMedGoogle Scholar
  3. 3.
    Dewey DL. 1971. The radiosensitivity of melanoma cells in culture. Br J Radiol 44:816.PubMedCrossRefGoogle Scholar
  4. 4.
    Weichselbaum RR, Nove J, Little JB. 1980. X-ray sensitivity of human tumor cells in vitro. Int J Radiat Oncol Biol Phys 6:437.PubMedCrossRefGoogle Scholar
  5. 5.
    McBride H, Stea B, Hill A, et al. 1990. Possible relationship between chromosome alterations and in vitro cellular radiosensitivity of human malignant melanoma. Int J Radiat Oncol Biol Phys 19:349.PubMedCrossRefGoogle Scholar
  6. 6.
    Rofstad EK. 1989. Local tumor control following single dose irradiation of human melanoma xenografts: Relationship of cellular radiosensitivity and influence of an immune response by the athymic mouse. Cancer Res 49:3163.PubMedGoogle Scholar
  7. 7.
    Trott KR, von Lieven H, Kummermehr J, et al. 1981. The radiosensitivity of malignant melanomas Part 1: Experimental studies. Int J Radiat Oncol Biol Phys 7:9.PubMedCrossRefGoogle Scholar
  8. 8.
    Rofstad EK, Brustad T. 1985. Tumor growth delay following single dose irradiation of human melanomas xenografts. Correlations with tumor growth parameters, vascular structure, and cellular radiosensitivity. Br J Cancer 51:201.PubMedCrossRefGoogle Scholar
  9. 9.
    Hall EJ. 1988. Radiobiology for the Radiologist. Philadelphia: JB Lippincott, pp 70.Google Scholar
  10. 10.
    Bristow RG, Hill RP. 1990. Comparison between in vitro radiosensitivity and in vivo radioresponse in murine tumor cell lines II: In vivo radioresponse following fractionated treatment and in vitro/in vivo correlations. Int J Radiat Oncol Biol Phys 18:331.PubMedCrossRefGoogle Scholar
  11. 11.
    Hall EJ. 1988. Radiobiology for the radiologist. Philadelphia: JB Lippincott, p 108.Google Scholar
  12. 12.
    Weichselbaum RR, Malcolm AW, Little JB. 1982. Fraction size and repair of potentially lethal radiation damage in a human melanoma cell line: Possible implications for radiotherapy. Radiology 142:225.PubMedGoogle Scholar
  13. 13.
    Rofstad EK. 1981. Radiation response of the cells of a human malignant melanoma xenograft. Effect of hypoxic cell radiosensitizers. Radiat Res 87:670.PubMedCrossRefGoogle Scholar
  14. 14.
    Chavaundra N, Guichard M, Malaise E. 1981. Hypoxic fraction and repair of potentially lethal radiation damage in two human melanomas transplanted into nude mice. Radiat Res 88:56.CrossRefGoogle Scholar
  15. 15.
    Marchese MJ, Minarik L, Hall EJ, et al. 1985. Potentially lethal damage repair in cell lines of radioresistant human tumors in normal skin fibroblasts. Int J Radiat Biol Phys 48:431–439.CrossRefGoogle Scholar
  16. 16.
    Hall EJ, Marchese M, Hei TK, et al. 1988. Radiation response characteristics of human cells in vitro. Radiat Res 114:415.PubMedCrossRefGoogle Scholar
  17. 17.
    Weichselbaum RR, Beckett M. 1987. The maximum recovery potential of human tumor cells may predict clinical outcome in radiotherapy. Int J Radiat Oncol Biol Phys 13:709.PubMedCrossRefGoogle Scholar
  18. 18.
    Weichselbaum RR, Dahlberg W, Little JB. 1985. Inherently radioresistant cells exist in some tumors. Proc Natl Acad Sci 82:4732.PubMedCrossRefGoogle Scholar
  19. 19.
    Ho VC, Sober AV. 1990. Therapy for cutaneous melanoma: An update. J Am Acad Dermatol 22:156.Google Scholar
  20. 20.
    Balch CM, Houghton A, Peters L. 1989. In VT Devita, S Hellman, SA Rosenberg (eds), Cutaneous melanoma. Cancer Principles & Practice of Oncology. Philadelphia: JB Lippincott, pp 1499–1542.Google Scholar
  21. 21.
    Harwood AR. 1983. Conventional fractionated radiotherapy for 51 patients with lentigo maligna and lentigo maligna melanoma. Int J Radiat Oncol Biol Phys 9:1019.PubMedCrossRefGoogle Scholar
  22. 22.
    Kopf AW, Bart RS, Gladstein AH. 1976. Treatment of melanotic freckle with X-rays. Arch Dermatol 112:801.PubMedCrossRefGoogle Scholar
  23. 23.
    Adair F. 1936. Treatment of melanoma: Report of four hundred cases, Surg Gynecol Obstet 62:406.Google Scholar
  24. 24.
    Tod MC. 1946. Radiological treatment of malignant melanoma. Br J Radiol 19:223.PubMedCrossRefGoogle Scholar
  25. 25.
    Sylven B. 1949. Malignant melanoma of the skin. Acta Radiol 32:33.PubMedCrossRefGoogle Scholar
  26. 26.
    Ellis F. 1939. The radiosensitivity of malignant melanomata. Br J Radiol 12:327.CrossRefGoogle Scholar
  27. 27.
    Hellriegel W. 1963. Radiation therapy of primary and metastatic melanoma. Ann NY Acad Sci 100:131.PubMedGoogle Scholar
  28. 28.
    Sealy R, Hockley J, Stepstone B. 1974. The treatment of malignant melanoma with cobalt and hyperbaric oxygen. Clin Radiol 25:211.PubMedCrossRefGoogle Scholar
  29. 29.
    Lobo PA, Liebner EJ, Chao JJ, et al. 1981. Radiotherapy in the management of malignant melanoma. Int J Radiat Oncol Biol Phys 7:21.PubMedCrossRefGoogle Scholar
  30. 30.
    Johanson CR, Harwood AR, Cummings BJ, et al. 1983. 0-7-21 radiotherapy in nodular melanoma. Cancer 51:226.PubMedCrossRefGoogle Scholar
  31. 31.
    Rounasville MD, Cantril ST, Fontanesi J, et al. 1988. Radiotherapy in the management of cutaneous melanoma: Effect of time, dose and fractionation. Front Radiat Ther Oncol 22:62.Google Scholar
  32. 32.
    Elsmann HJ, Ernst K, Suter L. 1991. Radiotherapy of primary human melanomas — experiences and suggestions. Strahlenther Onkol 167:387.PubMedGoogle Scholar
  33. 33.
    Harwood AR, Cummings BJ. 1981. Radiotherapy for malignant melanoma: A reappraisal. Cancer Treat Rev 8:271.PubMedCrossRefGoogle Scholar
  34. 34.
    Gottleib JA, Friei E, Luce JK. 1972. An evaluation of the management of patients with cerebral metastases from malignant melanoma. Cancer 29:701.CrossRefGoogle Scholar
  35. 35.
    Carella RJ, Gelber R, Hendrickson F, et al. 1980. Value of radiation therapy in the management of patients with cerebral metastases from malignant melanoma: RTOG brain metastases study I and II. Cancer 45:679.PubMedCrossRefGoogle Scholar
  36. 36.
    Katz HR. 1981. The relative effectiveness of radiation therapy, corticosteroids, and surgery in the management of melanoma metastatic to the central nervous system. Int J Radiat Oncol Biol Phys 7:897.PubMedCrossRefGoogle Scholar
  37. 37.
    Vlock DR, Kirkwood JM, Leutzinger C. 1982. High-dose fraction radiation therapy for intracranial metastases of malignant melanoma: A comparison with low-dose fraction therapy. Cancer 49:2289.PubMedCrossRefGoogle Scholar
  38. 38.
    Choi KN, Withers HR, Rotman M. 1985. Intracranial metastases from melanoma: Clinical features and treatment by accelerated fractionation. Cancer 56:1.PubMedCrossRefGoogle Scholar
  39. 39.
    Ziegler JC, Cooper JS. 1986. Brain metastases from malignant melanoma: Conventional vs. high-dose-per-fraction radiotherapy. Int J Radiat Oncol Biol Phys 12:1839.PubMedCrossRefGoogle Scholar
  40. 40.
    Retsas S, Gershuny AR. 1988. Central nervous system involvement in malignant melanoma. Cancer 61:1926.PubMedCrossRefGoogle Scholar
  41. 41.
    Rate WR, Solin LJ, Turrisi AT. 1988. Palliative radiotherapy for metastatic malignant melanoma: Brain metastases, bone metastases and spinal cord compression. Int J Radiat Oncol Biol Phys 15:859.PubMedCrossRefGoogle Scholar
  42. 42.
    Davey P, O’Brien P. 1991. Disposition of cerebral metastases from malignant melanoma: Implications for Radiosurgery. Neurosurgery 28:8.PubMedCrossRefGoogle Scholar
  43. 43.
    Stevens G, Firth I, Coates A. 1992. Cerebral metastases from malignant melanoma. Radiother Oncol 23:185.PubMedCrossRefGoogle Scholar
  44. 44.
    Strauss A, Dritschillo A, Nathanson L, et al. 1981. Radiation therapy of malignant melanomas: An evaluation of clinically used fractionation schemes. Cancer 47:1262.PubMedCrossRefGoogle Scholar
  45. 45.
    Cooper JS, Carella R. 1980. Radiotherapy of intracerebral metastatic malignant melanoma. Radiology 134:735.PubMedGoogle Scholar
  46. 46.
    Koenfal JB, Emami B, Pilepich MV. 1988. Analysis of dose fractionation in the palliation of metastases from malignant melanoma. Cancer 61:243.CrossRefGoogle Scholar
  47. 47.
    Choi KN, Withers HR, Rotman M. 1985. Metastatic melanoma in brain: Rapid treatment or large dose fractions. Cancer 56:10.PubMedCrossRefGoogle Scholar
  48. 48.
    Hilaris BS, Raben M, Calabrese AS. 1963. Value of radiation therapy for distant metastases from malignant melanoma. Cancer 16:765.PubMedCrossRefGoogle Scholar
  49. 49.
    Hagen NA, Cirrincione C, Thaler HT, et al. 1990. The role of radiation therapy following resection of single brain metastases from melanoma. Neurology 40:158.PubMedCrossRefGoogle Scholar
  50. 50.
    Oredsson S, Ingvar C, Stromblad L, et al. 1990. Palliative surgery for brain metastases of malignant melanoma. Eur J Surg Oncol 16:451.PubMedGoogle Scholar
  51. 51.
    Brega K, Robinson WA, Winston K, et al. 1990. Surgical treatment of brain metastases of malignant melanoma. Cancer 66:2105.PubMedCrossRefGoogle Scholar
  52. 52.
    Patchell RA, Tibbs PA, Walsh JW, et al. 1990. A randomized trial of surgery in the treatment of single metatases to the brain. N Engl J Med 322:494.PubMedCrossRefGoogle Scholar
  53. 53.
    Gilbert RW, Kim J, Posner JB. 1978. Epidural spinal cord compression from metastatic tumor: Diagnosis and treatment. Ann Neurol 3:40.PubMedCrossRefGoogle Scholar
  54. 54.
    Herbert SH, Solin LJ, Rate WR, et al. 1991. The effect of palliative radiotherapy on epidural compression due to metastatic malignant melanoma. Cancer 67:2472.PubMedCrossRefGoogle Scholar
  55. 55.
    Kagan AR. 1992. Radiation therapy in palliative cancer management. In CA Perez, LW Brady (eds), Principles and Practice of Radiation Oncology. Philadelphia: JB Lippincott, p 1500.Google Scholar
  56. 56.
    Katz HR. 1981. The results of different fractionation schemes in the palliative irradiation of metastatic melanoma. Int J Radiat Oncol Biol Phys 7:907.PubMedCrossRefGoogle Scholar
  57. 57.
    Habermalz HJ, Fischer JJ. 1976. Radiation therapy of malignant melanoma: Experience with high individual treatment doses. Cancer 38:2258.PubMedCrossRefGoogle Scholar
  58. 58.
    Overgaard J, Overgaard M, Hansen PV, et al. 1986. Some factors of importance in the radiation treatment of malignant melanoma. Radiat Oncol 5:183.CrossRefGoogle Scholar
  59. 59.
    Trott KR, von Lieven H, Kummermehr J, et al. 1981. The radiosensitivity of malignant melanomas. Part II: Clinical Studies. Int J Radiat Oncol Biol Phys 7:15–20.PubMedCrossRefGoogle Scholar
  60. 60.
    Overgaard J. 1986. The role of radiotherapy in recurrent and metastatic malignant melanoma: A clinical radiobiological study. Int J Radiat Oncol Biol Phys 12:867.PubMedCrossRefGoogle Scholar
  61. 61.
    Doss LL, Memula N. 1982. The radioresponsiveness of melanoma. Int J Radiat Oncol Biol Phys 8:1131.PubMedCrossRefGoogle Scholar
  62. 62.
    Overgaard J, von der Maase H, Overgaard M. 1985. A randomized study comparing two high-dose per fraction radiation schedules in recurrent or metastatic malignant melanoma. Int J Radiat Oncol Biol Phys 11:1837.PubMedCrossRefGoogle Scholar
  63. 63.
    Bentzen SM, Overgaard J, Thames HD, et al. 1989. Clinical radiobiology of malignant melanoma. Radiat Oncol 16:169.CrossRefGoogle Scholar
  64. 64.
    Hornsey S. 1978. The relationship between total dose, number of fractions and fraction size in the response of malignant melanoma in patient. Br J Radiat 51:905.CrossRefGoogle Scholar
  65. 65.
    Overgaard J. 1989. The current and potential role of hyperthermia in radiotherapy, Int J Radiat Oncol Biol Phys 16:535.PubMedCrossRefGoogle Scholar
  66. 66.
    Wambersie A. 1990. Fast neutron therapy at the end of 1988 — a survey of the clinical data. Strahlenther Onkol 166:52.PubMedGoogle Scholar
  67. 67.
    Blake PR. 1987. The treatment of malignant melanoma by fast neutrons. In L Nathanson (ed), Basic and Clinical Aspects of Malignant Melanoma. Boston: Martinus Nijhoff, pp 195–213.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1993

Authors and Affiliations

  • Michael J. Dougherty
  • Morton M. Kligerman

There are no affiliations available

Personalised recommendations