Effect of Host Proteases on Early Steps of Enterovirus Infection
Abstract
Enteroviruses, a genus in the family of Picornaviridae,are small non-enveloped animal viruses with a messenger-sense genomic RNA and an icosahedral capsid composed of 60 copies each of four structural proteins.1 There are about 70 different serotypes of enteroviruses isolated from man and a lot of others that infect domestic or wild animals. Because of their significance in public health the three serotypes of polioviruses, the causative agents of poliomyelitis, have been as targets of the most intensive research during the last a few decades. Other enteroviruses, although known for long to be medically important as well, have only recently acquired more specific attention. These studies have revealed interesting individual characteristics of various non-polio enteroviruses on top of the previously known antigenic differences.1–4
Keywords
Capsid Protein Antigenic Site Inoculum Virus Enterovirus Infection Poliovirus TypePreview
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References
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