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Dermal Absorption of Peptides and Proteins

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Biological Barriers to Protein Delivery

Part of the book series: Pharmaceutical Biotechnology ((PBIO,volume 4))

Abstract

Historically, the skin was viewed as an impermeable barrier. However, in recent years, it has been increasingly recognized that intact skin can be used as a port for continuous systemic administration of drugs. The first transdermal drug delivery system which has used this new concept is a scopolamine-releasing transdermal therapeutic system (Transderm-Scop® by Ciba) for motion sickness. This was followed by the marketing of several nitroglycerin-releasing systems. Currently, about ten drugs have been either successfully marketed or are under clinical evaluation for transdermal delivery.

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Author information

Author notes

  1. Ajay K. Banga

    Present address: Department of Pharmacal Sciences, School of Pharmacy, Auburn University, Auburn, Alabama, 36849, USA

Authors and Affiliations

  1. Controlled Drug-Delivery Research Center, College of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey, 08855, USA

    Ajay K. Banga & Yie W. Chien

Authors
  1. Ajay K. Banga
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  2. Yie W. Chien
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Editor information

Editors and Affiliations

  1. University of Kansas, Lawrence, Kansas, USA

    Kenneth L. Audus

  2. The Upjohn Company, Kalamazoo, Michigan, USA

    Thomas J. Raub

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© 1993 Springer Science+Business Media New York

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Banga, A.K., Chien, Y.W. (1993). Dermal Absorption of Peptides and Proteins. In: Audus, K.L., Raub, T.J. (eds) Biological Barriers to Protein Delivery. Pharmaceutical Biotechnology, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2898-2_8

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  • DOI: https://doi.org/10.1007/978-1-4615-2898-2_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6256-2

  • Online ISBN: 978-1-4615-2898-2

  • eBook Packages: Springer Book Archive

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