Molecular Aspects of the Control of Myocardial Relaxation

  • Ichiro Shiojima
  • Issei Komuro
  • Tsutomu Yamazaki
  • Ryozo Nagai
  • Yoshio Yazaki
Chapter

Abstract

Hemodynamic overload induces left ventricular hypertrophy as a result of individual myocyte growth {1} and isozymic changes in the composition of contractile proteins {2,3}. However, myocytes form only one third of all cells in myocardium, and the remaining two thirds are nonmyocytes, including fibroblasts, vascular smooth muscle cells, and endothelial cells {1,4}. The remodeling of interstitial components, as well as that of myocytes, has been demonstrated to occur during the process of cardiac hypertrophy {5}.

Keywords

Sarcoplasmic Reticulum Cardiac Hypertrophy Pressure Overload Cardiac Fibroblast Myocardial Relaxation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Ichiro Shiojima
  • Issei Komuro
  • Tsutomu Yamazaki
  • Ryozo Nagai
  • Yoshio Yazaki

There are no affiliations available

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