Skip to main content
SpringerLink
Log in

Intra- and Inter-Chain Disulfide Bridges of J Chain in Human S-IgA

  • Chapter
Advances in Mucosal Immunology

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 371))

Abstract

S-IgA is synthesized in two steps. First the IgA dimer is linked to the J chain, and afterwards the (IgA)2 J complex is linked to the Secretory Component (SC). Both linkages are accomplished by disulfide exchange and occur at different sites. The linkage of the J chain to IgA is the pre-requisit for the linkage of the SC to the IgA dimer.1

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. P. Brandtzaeg and H. Prydz, Nature 311: 71 (1984).

    Article  PubMed  CAS  Google Scholar 

  2. C. S. Pincus, M. E. Lamm, and V. Nussenzweig, J. Exp. Med. 133: 987 (1971).

    Article  PubMed  CAS  Google Scholar 

  3. A. G. Plaut, R. J. Genco, and T. B. Tomasi, Jr., J. Immunol 113: 289 (1974).

    CAS  Google Scholar 

  4. Ch. Y. Yang, H. Kratzin, H. Totz, and N. Hilschmann, Hoppe-Seyler’s Z. Physiol Chem. 360: 1919 (1979).

    Google Scholar 

  5. E. E. Max and S. J. Korsmeyer, J. Exp. Med. 161: 832 (1985).

    Article  PubMed  CAS  Google Scholar 

  6. R. B. Doumashkin, G.Virella, and R. M. E. Parkhouse, J. Mol Biol 56: 207 (1971)

    Article  Google Scholar 

  7. E. Fallgren-Gebauer, W. Gebauer, A. Bastian, H. Kratzin, H. Eiffert, B. Zimmermann, M. Karas, and N. Hilschmann, These Proceedings.

    Google Scholar 

  8. G. M. Cann, A. Zaritsky, and M. E. Koshland, Proc. Natl Acad. Sci. USA 79: 6656 (1982).

    Article  PubMed  CAS  Google Scholar 

  9. J. Zikan, J. Novotny, T. L. Trapane, M. E. Koshland, D. W. Urry, J. C. Bennett, and J. Mestecky, Proc. Natl Acad. Sci. USA 82: 5905 (1985).

    Article  PubMed  CAS  Google Scholar 

  10. R. S. H. Pumphrey, Immunol Today 7: 206 (1986).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Max-Planck-Institute for Experimental Medicine, Hermann-Rein-Straße 3, W3400, Göttingen, Germany

    A. Bastian, H. Kratzin, E. Fallgren-Gebauer, K. Eckart & N. Hilschmann

Authors
  1. A. Bastian
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Kratzin
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. Fallgren-Gebauer
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. K. Eckart
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. N. Hilschmann
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of Alabama at Birmingham, Birmingham, Alabama, USA

    Jiri Mestecky , Michael W. Russell , Susan Jackson  & Suzanne M. Michalek , ,  & 

  2. Academy of Sciences of the Czech Republic, Prague, Czech Republic

    Helena Tlaskalová-Hogenová  & Jaroslav Šterzl  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1995 Springer Science+Business Media New York

About this chapter

Cite this chapter

Bastian, A., Kratzin, H., Fallgren-Gebauer, E., Eckart, K., Hilschmann, N. (1995). Intra- and Inter-Chain Disulfide Bridges of J Chain in Human S-IgA. In: Mestecky, J., Russell, M.W., Jackson, S., Michalek, S.M., Tlaskalová-Hogenová, H., Šterzl, J. (eds) Advances in Mucosal Immunology. Advances in Experimental Medicine and Biology, vol 371. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1941-6_122

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-1941-6_122

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5796-4

  • Online ISBN: 978-1-4615-1941-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation