The Cell Biology of Coronavirus Infection

  • Erik Prentice
  • Mark R. Denison
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 494)


Several aspects of Coronavirus interaction with host cells have been identified, the best characterized of which involve virus entry and virion assembly (for review, see Holmes and Lai, 1996). These accomplishments are critical in the understanding of virus-cell interactions; however, since such interactions occur in four dimensions (over time in the three dimensional space of the cell) they are important landmarks on a path that for the most part remains unilluminated. To understand the dynamic relationship of the virus to the cell it is important to use approaches that can observe interactions in the context of the entire cell and throughout the course of infection.


Green Fluorescent Protein Virion Assembly Cytoskeletal Element Replication Complex Syncytium Formation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Erik Prentice
    • 1
  • Mark R. Denison
    • 1
  1. 1.Departments of Microbiology & Immunology and Pediatrics and The Elizabeth B. Lamb Center for Pédiatric ResearchVanderbilt University Medical CenterNashvilleUSA

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