Characterization of Nucleocapsid-M Protein Interaction in Murine Coronavirus

  • Krishna Narayanan
  • Shinji Makino
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 494)


Coronavirus is a large enveloped virus containing a 27-32 kb-long single-stranded, positive-sense RNA genome (Lee et al 1991). Coronaviruses generally have three envelope proteins S, M, and E. N protein and the viral genomic RNA form a helical nucleocapsid (Macnaughton et al 1978).


Northern Blot Analysis Salt Buffer Mouse Hepatitis Virus Viral Envelope Protein Sucrose Gradient Centrifugation 
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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Krishna Narayanan
    • 1
    • 2
  • Shinji Makino
    • 1
    • 2
  1. 1.Department of Microbiology, The Institute for Cellular and Molecular BiologyThe University of Texas at AustinAustinUSA
  2. 2.Department of Microbiology and ImmunologyThe University of Texas Medical Branch at GalvestonGalvestonUSA

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