A Virus-Neutralising Monoclonal Antibody Expressed in the Milk of Transgenic Mice
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Coronaviruses are frequently associated with respiratory and gastrointestinal disorders in both animals and man. In adult animals, Coronavirus infections are generally mild, however, in neonates they often cause severe and sometimes lethal diseases (Enjuanes and van der Zeijst, 1995). Maternal antibodies supplied via the placenta and milk efficiently protect new-born animals against the fatal consequences of acute coronaviral infections during this critical phase (Hornberger, 1992).
KeywordsTransgenic Mouse Recombinant Antibody Trans Gene Heavy Chain Variable Region Antibody Light Chain
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