Noninvasive Assessment of Trabecular Bone Architecture and the Competence of Bone

Volume 496 of the series Advances in Experimental Medicine and Biology pp 153-164

Visualization and Analysis of Trabecular Bone Architecture in the Limited Spatial Resolution Regime of In Vivo Micro-MRI

  • Felix W. Wehrli
  • , Scott N. Hwang
  • , Hee Kwon Song
  • , Bryon R. GombergAffiliated withLaboratory for Structural NMR Imaging, Department of Radiology, University of Pennsylvania Medical Center

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There is substantial evidence that besides the volume fraction of the bone (often quantified in terms of apparent bone density) the three-dimensional arrangement of the trabecular network is a major determinant of elastic modulus1-5and ultimate strength.6-8