Integrating Population Outcomes, Biological Mechanisms and Research Methods in the Study of Human Milk and Lactation pp 295-297 | Cite as
Milk Oligosaccharides Vary within Individuals and During Lactation
Abstract
Specific human milk oligosaccharides inhibit specific microbial pathogens.1 As soluble homologs or analogs of host receptors for pathogens, milk oligosaccharides, especially fucosylated neutral oligosaccharides, may act as decoys to protect infants against disease.2-4 To study a relationship between specific human milk oligosaccharides and disease in breast-fed infants, it is necessary to know the levels of specific oligosaccharides present in milks of individuals during lactation. Variation in total oligosaccharides, specific α1,2-linked oligosaccharides, and activities of fucosidases and fucosyltransferases has been reported.5, 6This study measures variation in individual fucosylated oligosaccharides in milks of individual mothers over the course of lactation.
Keywords
Human Milk Host Receptor Milk Oligosaccharide Human Milk Oligosaccharide Neutral OligosaccharidePreview
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