Cross Talk between Haematopoiesis and Angiogenesis

  • Domenico Ribatti
  • Angelo Vacca
  • Beatrice Nico
  • Enrico Crivellato
  • Giuseppe De Falco
  • Marco Presta
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 522)

Abstract

The relationship between endothelial cells (EC) and haematopoietic cells (HC) has been seen as an indication that a common progenitor, the haemangioblast, gives rise to both cell types in the yolk sac, the initial site of haematopoiesis and of blood vessel formation (Murray, 1934). Generation of haemangioblasts take place from embryonic stem cells (ESC) or from yolk sac blood islands or from intraembryonic AGM (aortagonad-mesonephros) region, containing the dorsal aorta, genital ridge/gonads and promesonephros.

Keywords

Vascular Endothelial Growth Factor Multiple Myeloma Conditioned Medium Antiangiogenic Activity Mast Cell Density 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bertolini, F., Mancuso, P., Gobbi, A., and Pruneri, G., 2000. The thin red line: angiogenesis in normal and malignant hematopoiesis.Exp. Hematol.28: 993–1000.PubMedCrossRefGoogle Scholar
  2. Choi, K., Kennedy, M., Kazarov, A., Papadimitriou, J.C., and Keller, G., 1998. A common precursor for hematopoietic and endothelial cells.Development125: 725–732.PubMedGoogle Scholar
  3. Coussens, L.M., and Werb, Z., 1996. Matrix metalloproteinases and the development of cancer.Chemic. Biol. 3895–904.CrossRefGoogle Scholar
  4. Fidler, I.J., and Ellis, L.M., 2000. Chemotherapeutic drugs - more really is not better.Nature Med.6: 500–502.PubMedCrossRefGoogle Scholar
  5. Folkman, J., 1971. Tumor angiogenesis: therapeutic implications.New Engl. J. Med.285: 1182–1186.PubMedCrossRefGoogle Scholar
  6. Folkman, J., 1990. What is the evidence that tumors are angiogenesis dependent?J. Nat!. Cancer Inst.22: 4–6.CrossRefGoogle Scholar
  7. Folkman, J., 1995. Clinical applications of research in angiogenesis.N. Engl. J. Med. 333:1757–1763.PubMedCrossRefGoogle Scholar
  8. Hanahan, D., and Folkman, J., 1996. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis.Cell86: 353–364.PubMedCrossRefGoogle Scholar
  9. Johnson, L.L., Dyer, R., and Hupe; D.J., 1998. Matrix metalloproteinases.Curr. Opin. Chem. Biol.4: 466–471.CrossRefGoogle Scholar
  10. Kerbel, R.S., 2000. Tumor angiogenesis: past, present and the near future.Carcinogenesis21: 505–515.PubMedCrossRefGoogle Scholar
  11. Mangi, M.H., and Newland, A.C., 2000. Angiogenesis and angiogenic mediators in haematological malignancies.Br. J. Haematol. 111:43–51.PubMedCrossRefGoogle Scholar
  12. Murray, P.D.F., 1934. The developmentin vitroof blood of the chick embryo.Proc. R. Soc. B111: 497–524.CrossRefGoogle Scholar
  13. Palis, J., Chan, R.J., Koniski, A., Patel, R., Starr, M., and Yoder, M.C., 2001. Spatial and temporal emergence of high proliferative potential haematopoietic precursors during murine embryogenesis.Proc. Natl. Acad. Sci. USA98: 4528–4533.PubMedCrossRefGoogle Scholar
  14. Park, C.C., Bissell, M.J., and Barcellos-Hoff, M.H., 2000. The influence of the microenvironment on the malignant phenotype.Mol. Med. Today6: 324–329.PubMedCrossRefGoogle Scholar
  15. Presta, M., Rusnati, M., Belleri, M., Morbidelli, L., Ziche, M., and Ribatti, D., 1999. Purine analogue 6methylmercaptopurine riboside inhibits early and late phases of the angiogenic process.Cancer Res.59: 2417–2424.PubMedGoogle Scholar
  16. Presta, M.. Belleri, M., Vacca, A., and Ribatti, D., 2002. Anti-angiogenic activity of the purine analog 6thioguanine. Leukemia, in press.Google Scholar
  17. Ribatti, D., Vacca, A., Nico, B., Fanelli, M., Roncali, L., and Dammacco, F., 1996. Angiogenesis spectrum in the stroma of B-cell non-Hodgkin’s lymphomas. An immunihistochemical and ultrastructural study.Eur. J. Haematol.56: 45–53.Google Scholar
  18. Ribatti, D., Nico, B., Vacca, A., Marzullo, A., Calvi, N., Roncali, L., and Dammacco, F., 1998. Do mast cells help to induce angiogenesis in B-cell non Hodgkin’s lymphomas?Br. J. Cancer77: 1900–1906.PubMedCrossRefGoogle Scholar
  19. Ribatti, D., Presta, M., Vacca, A., Ria, R., Giuliani, R., Dell’Era, P., Nico, B., Roncali, L., and Dammacco, F., 1999. Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularizationin vivo Blood93: 2627–2636.Google Scholar
  20. Ribatti, D., Vacca, A., Roncali, L., and Dammacco, F., 2000. Hematopoiesis and angiogenesis: a link between two apparently independent processes.J. Hematother. Stem Cell Res.9: 13–19.PubMedCrossRefGoogle Scholar
  21. Ribatti, D., Vacca, A., Marzullo, A., Nico, B.. Ria, R., Roncali, L., and Dammacco, F.. 2000. Angiogenesis and mast cell density with tryptase activity increase simultaneously with pathological progression in B-cell non-Hodgkin’s lymphomas.Int. J. Cancer85: 171–185.PubMedGoogle Scholar
  22. Ribatti, D., Vacca, A.. Nico. B., Crivellato, E., Roncali, L., and Dammacco, F., 2001. The role of mast cells in tumour angiogenesis.Br. J. Haematol.115: 514–521.PubMedCrossRefGoogle Scholar
  23. Ribatti, D., Polimeno, G.. Vacca, A., Marzullo, A., Crivellato, E.. Nico. B., Lucarelli. G., and Dammacco. F., 2002. Correlation of bone marrow angiogenesis and mast cells with tryptase activity in myelodysplastic syndromes. Leukemia, in pressGoogle Scholar
  24. Talks, K.L., and Harris, A.L., 2000. Current status of antiangiogenic factors. Br.J. Haematol.109: 477–489.PubMedCrossRefGoogle Scholar
  25. Vacca, A., Ribatti, D., Roncali, L., Serio, G., Silvestris, F., and Dammacco, F., 1994. Bone marrow angiogenesis and progression in multiple myeloma.Br. J. Haematol.87: 503–508.PubMedCrossRefGoogle Scholar
  26. Vacca, A., Ribatti, D., lurlaro, M., Albini, A.. Minischetti, M., Bussolino, F., Pellegrino, A., Ria, R., Rusnati, M., Presta, M., Vincenti. V., Persico. M.G., and Dammacco, F., 1998. Human lymphoblastoid cells produce extracellular matrix-degrading enzymes and induce endothelial cell proliferation, migration, morphogenesis and angiogenesis.Int. J. Clin. Lab. Res.28: 55–68.PubMedCrossRefGoogle Scholar
  27. Vacca. A., Ribatti, D., Presta. M., Minischetti, M., lurlaro, M., Ria, R., Albini. A.. Bussolino, F., and Dammacco, F.. 1999. Bone marrow neovascularization, plasma cell angiogenic potential and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma.Blood93: 3064–3073.PubMedGoogle Scholar
  28. Vacca, A., lurlaro, M., Ribatti, D., Minischetti. M.. Nico, B.. Ria, R.. Pellegrino. A.. and Dammacco, F., 1999. Antiangiogenesis is produced by nontoxic doses od vinblastine.Blood94: 4143–4155.PubMedGoogle Scholar
  29. Vacca, A., Ribati, D., lurlaro, M., Merchionne, F.. Nico, B., Ria, R.. and Dammacco, F., 2002. Docetaxel versus paclitaxel for antiangiogenesis.J. Hematother. Stem Cell Res.11: 103–118.PubMedCrossRefGoogle Scholar
  30. Valdembri. D., Serini, G., Vacca, A., Ribatti. D.. and Bussolino. F., 2002.In tiroactivation of JAK-2/STAT-3 pathway during angiogenesis induced by GM-CSF.FASEB J.16 225–227.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Domenico Ribatti
    • 1
  • Angelo Vacca
    • 2
  • Beatrice Nico
    • 1
  • Enrico Crivellato
    • 3
  • Giuseppe De Falco
    • 2
  • Marco Presta
    • 4
  1. 1.Department of Human Anatomy and HistologyUniversity of Bari Medical School, PoliclinicoBariItaly
  2. 2.Department of Biomedical Sciences and Human OncologyUniversity of Bari Medical School, PoliclinicoBariItaly
  3. 3.Department of Medical and Morphological Researches, Section of AnatomyUniversity of Udine Medical SchoolUdineItaly
  4. 4.Unit of General Pathology and Immunology, Department of Biomedical Sciences and BiotechnologyUniversity of Brescia Medical SchoolBresciaItaly

Personalised recommendations