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Monitoring the EEG for Assessing Depth of Anesthesia

  • Guy A. DumontEmail author
Chapter

Abstract

The action of anesthetic drugs on the brain is reflected by changes in the electrical activity of the brain, as measured by scalp electroencephalography (EEG). Typically, anesthetics lead to a larger and slower EEG activity. Although this has been known for many decades, it is only in the last 15 years or so that monitors for intraoperative brain monitoring have become commercially available. This chapter presents the basic principles behind five of those monitors, discussing their use and limitations.

Keywords

State Entropy Anesthetic State Spectral Edge Frequency Response Entropy Hypnotic State 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Conflict of Interest Statement

GA Dumont is coinventor of the NeuroSENSE monitor (NeuroWave Systems Inc., Cleveland, OH). He has consulted for NeuroWave Systems Inc and GE Healthcare.

References

  1. 1.
    Collura TF. History and evolution of electroencephalographic instruments and techniques. J Clin Neurophysiol. 1993;10(4):476–504.PubMedCrossRefGoogle Scholar
  2. 2.
    Caton R. The electric currents of the brain. Br Med J. 1875;2:278.Google Scholar
  3. 3.
    Berger H. Über das Elektrenkephalogramm des Menschen. Arch Psychiatr Nervenkr. 1929;87:527–70.CrossRefGoogle Scholar
  4. 4.
    Gibbs FA, Gibbs EL, Lenox WG. Effect on electroencephalogram of certain drugs which influence nervous activity. Arch Intern Med. 1937;60:154–66.CrossRefGoogle Scholar
  5. 5.
    Kiersey DK, Bickford RG, Faulconer Jr A. Electro-encephalographic patterns produced by thiopental sodium during surgical operations; description and classification. Br J Anaesth. 1951;23:141–52.PubMedCrossRefGoogle Scholar
  6. 6.
    Vanderwolf CH. Are neocortical gamma waves related to consciousness? Brain Res. 2000;855(2):217–24.PubMedCrossRefGoogle Scholar
  7. 7.
    Brown EN, Lydic R, Schiff ND. General anesthesia, sleep and coma. N Engl J Med. 2010;363:2638–50.PubMedCrossRefGoogle Scholar
  8. 8.
    Hudetz A. Cortical disintegration mechanism of anesthetic-induced unconsciousness. In: Hudetz A, Pearce R, editors. Suppressing the mind. New York: Humana Press; 2010.CrossRefGoogle Scholar
  9. 9.
    Rampil H, Lockhart SH, Eger 2nd EI, Yasuda N, Weiskopf RB, Cahalan MK. The electroencephalographic effects of desflurane in humans. Anesthesiology. 1991;74:434–9.PubMedCrossRefGoogle Scholar
  10. 10.
    Rampil IJ. A primer for EEG signal processing in anesthesia. Anesthesiology. 1998;89:980–1002.PubMedCrossRefGoogle Scholar
  11. 11.
    Viertö-Oja H, Maja V, Särkelä M, Talja P, Tenkanen N, Tolvanen-Laakso H, et al. Description of the entropy algorithm as applied in the Datex-Ohmeda S/5 entropy module. Acta Anaesthesiol Scand. 2004;48:154–61.CrossRefGoogle Scholar
  12. 12.
    Kreuer S, Wilhelm W. The Narcotrend monitor. Best Pract Res Clin Anaesthesiol. 2006;20(1):111–9.PubMedCrossRefGoogle Scholar
  13. 13.
    Zikov T, Bibian S, Dumont GA, Huzmezan M, Ries CR. Quantifying cortical activity during general anesthesia using wavelet analysis. IEEE Trans Biomed Eng. 2006;53(4):617–32.PubMedCrossRefGoogle Scholar
  14. 14.
    Prichep LS, Gugino LD, John ER, Chabot RJ, Howard B, Merkin H, et al. The patient state index as an indicator of the level of hypnosis under general anesthesia. Br J Anaesth. 2004;92(3):393–9.PubMedCrossRefGoogle Scholar
  15. 15.
    Bibian S, Dumont GA, Zikov T. Dynamic behavior of BIS, M-entropy and NeuroSENSE brain function monitors. J Clin Monit Comput. 2011;25(1):81–7.PubMedCrossRefGoogle Scholar
  16. 16.
    Otto KA. EEG power spectrum analysis for monitoring depth of anaesthesia during experimental surgery. Lab Anim. 2008;42:45–61.PubMedCrossRefGoogle Scholar
  17. 17.
    Ellerkman RK, Grass A, Hoeft A, Soehle M. The response of the composite variability index to a standardized noxious stimulus during propofol-remifentanil anesthesia. Anesth Analg. 2013;116(3):580–8.CrossRefGoogle Scholar
  18. 18.
    Schell R, Cole D, Lichtor JL, Miller R. Neurophysiologic monitors. In: Atlas of anesthesia, vol. 3. New York: Current Medicine; 2002.Google Scholar
  19. 19.
    Patel S, White D, Collop N, Crapo J. Bone’s atlas of pulmonary and critical care medicine. New York: Current Medicine; 2002.Google Scholar

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of Electrical and Computer EngineeringUniversity of British ColumbiaVancouverCanada

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