Vitrification of Oocytes: From Basic Science to Clinical Application

  • Amir AravEmail author
  • Yehudit Natan
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 761)


Vitrification is a physical process by which a liquid is transformed into a solid of amorphous glass form. It was only at the end of the nineteenth century (1898) that Gustav Heinrich Johann Apollon Tammann pointed out that a large number of substances can be obtained as glasses and suggested that this property might be universal (Tammann, Zeitschrift for Physikalische Chemie; 25: 441–479, 1898). Basically, vitrification is the supercooling of a liquid to a temperature at which the viscosity is so high that it can be defined as being at a solid state. The understanding of the vitrification process has been deepened over the years and has been applied for cryopreservation and currently is the method of choice for preserving oocytes and embryos.


Vitrification Oocytes Embryos Cryopreservation Application 



I would like to thank Prof. Kui Liu for his suggestions and critical reading of the manuscript.


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© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.FertileSafeTel AvivIsrael

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