On the Development of Vaccine Antigen Databases: Progress, Opportunity, and Challenge

  • Hifzur Rahman Ansari
  • Darren R. Flower
  • Gajendra P. S. Raghava
Chapter
Part of the Immunomics Reviews: book series (IMMUN, volume 5)

Abstract

The accumulation of relevant and appropriate data is the essential preliminary to any successful informatics-based exercise in prediction. Without quality data, meaningful prediction is impossible. This is as true in immunobiology as it is in any other branch of the natural sciences. Within the context of vaccine discovery, the accumulation, storage, and retrieval of immunological data within publically accessible repositories, typically web-based databases, is of overwhelming operational importance. Specifically, and with the special reference to the discovery of subunit vaccines, this chapter explores the current state and status of immunological databases focussed on immunogenic proteins, primarily pathogen antigens and environmental allergens. It sets this exploration firmly into context by simultaneously scoping out the rather more mature backdrop provided by epitope-orientated database systems.

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Hifzur Rahman Ansari
    • 1
  • Darren R. Flower
    • 2
  • Gajendra P. S. Raghava
    • 1
  1. 1.Bioinformatics Centre, Institute of Microbial TechnologyChandigarhIndia
  2. 2.School of Life and Health SciencesAston UniversityBirminghamUK

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