Ganglioside Function pp 215-229 | Cite as
The Relationship Between the Action of Tetanus Toxin and its Binding by Membranes and Gangliosides
Chapter
Abstract
Tetanus toxin binds to synaptic membranes and to purified gan-gliosides in vitro (van Heyningen, 1959, a, b, c). Two questions have frequently arisen: 1) are gangliosides responsible for the binding of tetanus toxin to nervous tissue?; and 2) does toxin binding play a role in the lethal action of the toxin?
Keywords
Botulinum Toxin Nervous Tissue Synaptic Membrane Tetanus Toxin Toxin Concentration
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