Assessment of Corneal Deformation Using Optical Coherence Tomography and Digital Volume Correlation
In order to study the mechanical behavior of the vertebrate eye cornea under intraocular pressure, digital volume correlation (DVC) has been carried out on a series of volume images generated through swept source optical coherence tomography (SSOCT). Phantom and porcine cornea samples under posterior inflation conditions were considered. The effect of noise and reconstruction uncertainties were evaluated through correlation of two repeated reconstructed volumes without loading. The strain resolutions of the DVC were obtained after calculating their mean and standard deviation values. Then, several reconstructed volumes were recorded one after the other, introducing a rigid body translation of 10 μm between successive volume images and the mean and standard deviation of strain were also identified. The volume deformation process of both phantom and porcine cornea samples under inflation test from 2 to 2.25 kPa were then visualized and the distribution patterns of displacement and strain fields analyzed with a view to stiffness identification.
KeywordsDigital Volume Correlation (DVC) Swept Source Optical Coherence Tomography (SSOCT)