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Prenyldiphosphate Synthases and Gibberellin Biosynthesis

  • Chris C. N. van SchieEmail author
  • Michel A. Haring
  • Robert C. Schuurink
Chapter

Abstract

Gibberellins are derived from the diterpene precursor geranylgeranyl diphophosphate (GGPP). GGPP is converted to ent-kaurene, which contains the basic structure of gibberellins, in the plastids by the combined actions of copalyl diphosphate synthase (CPS) and ent-kaurene synthase (KS). Generally, geranylgeranyl diphosphate synthase (GGPS) is suggested to use isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) as substrates to generate the GGPP that is used by CPS.

In this chapter we will provide data to show that actually the activity of geranyl diphosphate synthase (GPS) is required in both tomato (Solanum lycopersicum) and Arabidopsis thaliana for the biosynthesis of gibberellins. This finding indicates that GGPS uses GPP and IPP as substrates to produce the GGPP precursor for gibberellin biosynthesis. We will also argue that the pool of GGPP that is used for the biosynthesis of gibberellins is different from those GGPP pools that are used for other terpenoid-based molecules. Through analysis of Arabidopsis microarray data we attempt to predict which member of the GGPS gene family is actually involved in gibberellin precursor biosynthesis.

Keywords

Terpene Gibberellin Tomato Arabidopsis Terpenoid precursors 

Notes

Acknowledgements

We thank Dr. Petra Bleeker for critically reading the manuscript.

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Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • Chris C. N. van Schie
    • 1
    Email author
  • Michel A. Haring
    • 2
  • Robert C. Schuurink
    • 2
  1. 1.Division of Biological SciencesUniversity of California, San DiegoLa JollaUSA
  2. 2.Department of Plant PhysiologySwammerdam Institute for Life SciencesAmsterdamThe Netherlands

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