Abstract
Urine is initially an ultrafiltrate of the plasma. Ultrafiltration occurs from the glomerulus (a tuft of capillaries) into the Bowman’s capsule (the blind end of a nephron)—see Fig. 3.1. In moving from the capillary into the Bowman’s capsule, the filtrate must traverse three layers. These are:
Keywords
Glomerular Filtration Rate Mesangial Cell Glomerular Capillary Oncotic Pressure Tubular Fluid
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Further Reading
- Haraldsson B, Nystrom J, Deen WM (2008) Properties of the glomerular barrier and mechanisms of proteinuria. Physiol Rev 88:451–487PubMedCrossRefGoogle Scholar
- Kriz W, Kaissling B (1992) Structural organization of the mammalian kidney. In: Seldin DW, Giebisch C (eds) The kidney: physiology and pathology. Raven Press, New YorkGoogle Scholar
- Tryggvason K, Wartiovaara J (2005) How does the kidney filter plasma? Physiology 20:96–101PubMedCrossRefGoogle Scholar
- Verroust PJ, Christensen EI (2002) Megalin and cubilin—the story of two multipurpose receptors unfolds. Nephrol Dial Transplant 17:1867–1871PubMedCrossRefGoogle Scholar
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© Springer Science+Business Media New York 2012