Effects of Aerobic Exercise on Mood and Human Opioidergic Activation Measured by Positron Emission Tomography

  • Henning BoeckerEmail author
  • Thomas R. Tölle
  • Michael Valet
  • Till Sprenger


According to the often-cited “endorphin hypothesis”, endogenous opioidergic transmitter release has been postulated as the neurochemical basis of some of the psychophysical effects associated with endurance exercise, in particular mood changes. This chapter provides an overview on the applicability of positron emission tomography (PET) ligand activation studies with opioidergic tracers for imaging endogenous opioidergic transmission associated with exercise.


Positron Emission Tomography Opioid Receptor Positron Emission Tomography Study Endurance Exercise Positron Emission Tomography Scan 
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Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • Henning Boecker
    • 1
    Email author
  • Thomas R. Tölle
    • 2
  • Michael Valet
    • 3
  • Till Sprenger
    • 4
  1. 1.Functional Neuroimaging Group, Department of RadiologyUniversity of BonnBonnGermany
  2. 2.Department of Neurology, Klinikum rechts der IsarTechnical University MunichMunichGermany
  3. 3.Department of Neurology, Klinikum rechts der IsarTechnical University MunichMunichGermany
  4. 4.Department of Neurology, Division of NeuroradiologyUniversity Hospital BaselBaselSwitzerland

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