Multifunctional Nanoparticles for Target-Specific Imaging and Therapy

  • Anita Gianella
  • Joanna C. Read
  • David P. Cormode
  • Zahi A. Fayad
  • Willem J. M. Mulder
Chapter
First Online:
Part of the Nanostructure Science and Technology book series (NST)

Abstract

Since the early 2000s, we have witnessed an explosive growth in the development, preclinical application, and funding opportunities of nanoparticle research in biomedicine. One of the latest advances in nanoparticle development for biomedical purposes includes multifunctionality. This may apply to different features, including the functionalization to enhance specificity, the integration of multiple drugs, and the inclusion of imaging labels. Combinations of inorganic, polymeric, and natural materials to create hybrid nanoparticles are also possible. The complexity of such nanoparticle platforms increases with the number of materials and functionalities added. In this chapter, we review the latest developments in the design and application of multifunctional hybrid nanoparticles.

Keywords

Gold Nanoparticles Silica Nanoparticles Magnetic Resonance Imaging Contrast Agent Hybrid Nanoparticles Hydrated Iron Oxide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Anita Gianella
    • 1
  • Joanna C. Read
    • 1
  • David P. Cormode
    • 1
  • Zahi A. Fayad
    • 1
  • Willem J. M. Mulder
    • 1
  1. 1.Translational and Molecular Imaging InstituteMount Sinai School of MedicineNew YorkUSA

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