Handbook of Endovascular Peripheral Interventions pp 141-150 | Cite as
Prevention of Contrast-Induced Nephropathy
Chapter
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Abstract
There is no consensus definition of contrast-induced nephropathy (CIN). Commonly used definitions include an increase in serum creatinine of 0.5 mg/dL or a 25% increase above baseline within 48 h of contrast.
Keywords
Sodium Bicarbonate Isotonic Saline Contrast Administration Livedo Reticularis High Dose Protocol
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Bibliography
- 1.Kagan A and D Sheikh-Hamad. Contrast-induced Kidney Injury: Focus on Modifiable Risk Factors and Prophylactic Strategies. Clin Cardiol. 2010; 33(2): 62–66. ® An excellent overview of risk factors, pathophysiology, and prevention of CIN. PubMedCrossRefGoogle Scholar
- 2.Jawdeh B, AA Kanso, JR Schelling. Evidence-based Approach for Prevention of Radiocontrast-induced Nephropathy. J Hosp Med. 2009 Oct; 4(8): 500–506. ® Another review of CIN with more in-depth discussion of CIN prophylaxis. PubMedCrossRefGoogle Scholar
- 3.Mehran R, ED Aymong, E Nikolsky, et al. A Simple Risk Score for Prediction of Contrast-Induced Nephropathy After Percutaneous Coronary Intervention: Development and Initial Validation. J Am Coll Cardiol. 2004 Oct 6; 44(7): 1393–1399. ® Provides a method to calculate risk of CIN based on patient risk factors. PubMedGoogle Scholar
- 4.Mueller C, G Buerkle, HJ Buettner et al. Prevention of contrast media-associated nephropathy. Arch Int Med. 2002; 162: 329–336. ® Prospective randomized controlled trial comparing isotonic saline vs. half-isotonic saline in prevention of contrast induced nephropathy. CrossRefGoogle Scholar
- 5.Merten GJ, WP Burgess, LV Gray, et al. Prevention of contrast-induced nephropathy with sodium bicarbonate. JAMA 2004; 291: 2328–2334. ® One of the first prospective trials showing IV sodium bicarbonate reduces the risk of CIN. Google Scholar
- 6.Hoste E, De Waele JJ, Gevaert SA, et al. Sodium bicarbonate for prevention of contrast-induced acute kidney injury: a systematic review and meta-analysis. Nephrol Dial Transplant. 2010; 25: 747–758. ® A recent meta-analysis showing reduced rates of CIN when using sodium bicarbonate vs. saline. PubMedCrossRefGoogle Scholar
- 7.Tepel M, vander Giet M, Schwarzfeld C et al. Prevention of radiographic-contrast-agent-induced reductions in renal function by acetylcysteine. N Engl J Med. 2000; 343: 180–4. ® First clinical trial showing benefit of NAC in CIN prevention. PubMedCrossRefGoogle Scholar
- 8.Trivedi H, S Daram, A Szabo, et al. High-dose N-acetylcysteine for the prevention of contrast-induced nephropathy. Am J Med. 2009; 122: 874.e9-874.e15. ® A meta-analysis showing benefit of high dose N-acetylcysteine for CIN prevention. Google Scholar
- 9.McCullough PA, Bertrand ME, Brinker JA, Stacul F. A meta-analysis of the renal safety of isoosmolar iodixanol compared with low-osmolar contrast media. J Am Coll Cardiol. 2006; 48(4): 692–699. ® A meta-analysis showing a lower rate of CIN with iodixanol (isoosmolar contrast) compared with low osmolar contrast media. PubMedCrossRefGoogle Scholar
- 10.Marenzi G, Marana I, Lauri G et al. The prevention of radiocontrast-agent-induced nephropathy by hemofiltration. N Engl J Med. 2003; 349: 1333–1340. ® Prospective clinical trial comparing CVVH vs. control to prevent contrast-induced nephropathy. PubMedCrossRefGoogle Scholar
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