How old are RNA Networks?

  • Toni Daly
  • X. Sylvia Chen
  • David Penny
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 722)

Abstract

Some major classes of RNAs (such as mRNA, rRNA, tRNA and RNase P) are ubiquitous in all living systems so are inferred to have arisen early during the origin of life. However, the situation is not so clear for the system of RNA regulatory networks that continue to be uncovered, especially in eukaryotes. It is increasingly being recognised that networks of small RNAs are important for regulation in all cells, but it is not certain whether the origin of these networks are as old as rRNAs and tRNA. Another group of ncRNAs, including snoRNAs, occurs mainly in archaea and eukaryotes and their ultimate origin is less certain, although perhaps the simplest hypothesis is that they were present in earlier stages of life and were lost from bacteria. Some RNA networks may trace back to an early stage when there was just RNA and proteins, the RNP-world; before DNA.

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Copyright information

© Landes Bioscience and Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Toni Daly
    • 1
    • 3
  • X. Sylvia Chen
    • 2
  • David Penny
    • 3
  1. 1.Allan Wilson Centre of Molecular Ecology and EvolutionMassey UniversityPalmerston NorthNew Zealand
  2. 2.Department of BiochemistryUniversity of OtagoDunedinNew Zealand
  3. 3.Institute of Molecular BioSciencesMassey UniversityPalmerston NorthNew Zealand

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