Cancer Associated Viruses

Part of the series Current Cancer Research pp 571-583


Hepatitis C Virus and Hepatocellular Carcinoma

  • Brett LindenbachAffiliated withSection of Microbial Pathogenesis, Yale University School of Medicine, 354C Boyer Center for Molecular Medicine Email author 

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Hepatitis C virus (HCV) is strongly linked with the development of hepatocellular carcinoma. However, cancer arises in only a subset of patients, and takes several years to develop. Thus, the role of HCV in the etiology of cancer has remained elusive. I summarize here the clinical and molecular virological connections between HCV and liver cancer.