The Role of Zinc in Candida Dimorphism

  • David R. Soll
Chapter
Part of the Current Topics in Medical Mycology book series (CT MYCOLOGY, volume 1)

Abstract

The yeast Candida albicans remains a persistent pathogen in humans (42). For reasons that still remain obscure, this commensal is able to sense changes in the physiology of the host, especially debilitating ones, and to attack opportunistically tissues ranging in diversity from vaginal epithelium to heart valve (2, 3, 4, 42, 45). Candida species are capable of growing in at least two distinct forms: the “yeast” or budding form and the elongate mycelial form (42). Both are found in infected tissue and both may play a role in the invasion process. Several mycelium-minus mutants have been found to be relatively nonvirulent (Buckley, personal communication), supporting the suggestion that the mycelium invades tissue.

Keywords

Candida Albicans Mother Cell Germ Tube Stationary Phase Cell Stationary Phase Culture 
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© Springer-Verlag New York, Inc. 1985

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  • David R. Soll

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