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Carcinoma Metastatic to the Thyroid Gland

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Malignant Tumors of the Thyroid

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Abstract

Carcinomas metastasizing from other organs to the thyroid gland were considered to be rare1,2 until the 1950s3–5 when several authors began reporting a significant incidence of this entity at autopsy as well as sporadic clinically apparent cases. As more attention has been paid to this phenomenon, more has been learned about it.6–32 The incidence, clinical picture, differential diagnosis, and treatment and prognosis are discussed below.

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References

  1. Willis RA. Metastatic tumors in the thyroid gland. Am J Pathol 1931; 7: 187–208.

    PubMed  CAS  Google Scholar 

  2. Rice CO. Microscopic metastases in the thyroid gland. Am J Pathol 1934; 10: 407–412

    PubMed  CAS  Google Scholar 

  3. Thorpe JD. Metastatic cancer in thyroid gland. Report of 4 cases. West J Surg 1954: 62: 574–576.

    PubMed  CAS  Google Scholar 

  4. Mortensen JD, Woolner LB, Bennet WA. Secondary malignant tumors of the thyroid gland. Cancer 1956; 9: 306–309.

    Article  PubMed  CAS  Google Scholar 

  5. Elliott RHE Jr, Frantz VR. Metastatic carcinoma masquerading as primary thyroid cancer: report of authors’ 14 cases. Ann Surg 1960; 151: 551–565.

    Article  PubMed  Google Scholar 

  6. Shimaoka K, Sokal J, Pickren J. Metastatic neoplasms in the thyroid gland. Cancer 1962; 15: 557–565.

    Article  PubMed  CAS  Google Scholar 

  7. Wychulis AR, Beahrs OH, Woolner LB. Metastatic carcinoma to the thyroid gland. Ann Surg 1964; 160: 169–177.

    Article  PubMed  CAS  Google Scholar 

  8. Brierre JT, Dickinson LG. Clinically unsuspected thyroid disease. GB 1964; 30: 94–98.

    Google Scholar 

  9. Silverberg SG, Vidone RA. Metastatic tumors in the thyroid. Pacif Med Surg 1966; 74: 175–180.

    Google Scholar 

  10. Sirota DK, Goldfield EB, Eng YF, Unger AH. Metastatic infiltration of the thyroid gland causing hypothyroidism. J. Mt. Sinai Hosp. 1968; 35: 242–245.

    CAS  Google Scholar 

  11. Gault EW, Leung TH, Thomas DP. Clear cell renal carcinoma masquerading as thyroid enlargement. J Pathol 1974; 113: 21–25.

    Article  PubMed  CAS  Google Scholar 

  12. Pillay SP, Angorn IB, Baker LW. Tumor metastases to the thyroid gland. S Afr Med J. 1977; 51: 509–512.

    PubMed  CAS  Google Scholar 

  13. Burge T, Lunberg S. Cancer in Malmo 1958–1969. An autopsy study. Acta Pathol Microbiol Scand 1977;Suppl:260.

    Google Scholar 

  14. Ericsson M, Biorklund A, Cederquist E, Ingemansson S, Akerman M. Surgical treatment of metastatic disease in the thyroid gland. J Surg Oncol 1981; 17: 15–23.

    Article  PubMed  CAS  Google Scholar 

  15. Treadwell T, Alexander BB, Owen M, McConnell TH, Ash Worth CT. Clear cell renal carcinoma masquerading as a thyroid nodule. South Med J 1981; 74: 878–879.

    Article  PubMed  CAS  Google Scholar 

  16. Czech JM, Lichtor TR, Carney JA, van Heerden JA. Neoplasms metastatic to the thyroid gland. Surg Gynecol Obstet 1982; 155: 503–505.

    PubMed  CAS  Google Scholar 

  17. Lehur PA, Cote RA, Poisson J, Boctor M, Elhilali M, Kandalaft N. Thyroid metastasis of clear-cell renal carcinoma. Can Med Assoc J 1983; 128: 154–158.

    PubMed  CAS  Google Scholar 

  18. Ivy HK. Cancer metastatic to the thyroid: a diagnostic problem. Mayo Clin Proc 1984; 59: 856–859.

    PubMed  CAS  Google Scholar 

  19. Eriksson A, Gezelius C. Metastatic choriocarcinoma during normal pregnancy presenting as thyroid tumor. Arch Gynecol 1984; 236: 119–122.

    Article  PubMed  CAS  Google Scholar 

  20. McCabe DP, Farrar WB, Petkov TM, Finkelmeier W, O’Dwyer P, James A. Clinical and pathologic correlations in disease metastatic to the thyroid gland. Am J Surg 1985; 150: 519–523.

    Article  PubMed  CAS  Google Scholar 

  21. Lasser A, Rothman JG, Calamia VJ. Renal-cell carcinoma metastatic to the thyroid-aspiration cytology and histologic findings. Acta Cytol 1985; 29: 856–858.

    PubMed  CAS  Google Scholar 

  22. Gherardi G, Scherini P, Ambrosi S. Occult thyroid metastatis from untreated uveal melanoma. Arch Ophthalmol 1985; 103: 689–691.

    PubMed  CAS  Google Scholar 

  23. Lester JW, Carter MP, Berens SV, Long RF, Caplan GE. Colon carcinoma metastatic to the thyroid gland. Clin Nucl Med 1986; 11: 634–635.

    Article  PubMed  Google Scholar 

  24. Smith SA, Gharib H, Goellner JR. Fine-needle aspiration. Usefulness for diagnosis and management of metastatic carcinoma to the thyroid. Arch Intern Med 1987; 147: 311–312.

    Article  PubMed  CAS  Google Scholar 

  25. Chacho MS, Greenebaum E, Moussouris HF, Schreiber K, Koss LG. Value of aspiration cytology of the thyroid in metastatic disease. Acta Cytol 1987; 31: 705–712.

    PubMed  CAS  Google Scholar 

  26. Hsu C, Boey J. Diagnostic pitfalls in fine needle aspiration of thyroid nodules a study of 555 cases in Chinese patients. Acta Cytol 1987; 31: 699–704.

    PubMed  CAS  Google Scholar 

  27. Watts NB. Carcinoma metastatic to the thyroid: prevalence and diagnosis by fine-needle aspiration cytology. Am J Med Sci 1987; 293: 13–17.

    Article  PubMed  CAS  Google Scholar 

  28. Krauth PH, Katz JF. Kaposi’s sarcoma involving the thyroid in a patient with AIDS. Clin Nucl Med 1987; 12: 848–849.

    Article  PubMed  CAS  Google Scholar 

  29. Ackerman L, Romyn A, Khedkar N, Kaplan E. Malignant fibrous histiocytoma metastatic to the thyroid gland. Clin Nucl Med 1987; 12: 648–649.

    Article  PubMed  CAS  Google Scholar 

  30. Gritsman AY, Popok SM, Ro JY, Dekmezian RH, Weber RS. Renal-cell carcinoma with intranuclear inclusions metastatic to thyroid: a diagnostic problem in aspiration cytology. Diagn Cytopathol 1988; 4: 125–129.

    Article  PubMed  CAS  Google Scholar 

  31. Green LK, Ro JY, MacKay B, Ayala AG, Luna MA. Renal cell carcinoma metastatic to the thyroid. Cancer 1989; 63: 1810–1815.

    Article  PubMed  CAS  Google Scholar 

  32. Bisi H, Fernandes VSO, Asato De Camargo RY, Koch L, Abado AH, DeBrito T. The prevalence of unsuspected thyroid pathology in 300 sequential autopsies, with special reference to the incidental carcinoma. Cancer 1989; 64: 1888–1893.

    Article  PubMed  CAS  Google Scholar 

  33. Abrams HL, Spiro R, Goldstein N. Metastases in carcinoma; analysis of 1000 autopsied cases. Cancer 1950; 3: 74–85.

    Article  PubMed  CAS  Google Scholar 

  34. Hazard JB, Kaufman N. A survey of thyroid glands obtained at autopsy in a so-called goiter area. Am J Clin Pathol 1952; 22; 860–865.

    PubMed  CAS  Google Scholar 

  35. Hull OH. Critical analysis of two hundred twenty one thyroid glands: Study of thyroid glands obtained at necropsy in Colorado. Arch Pathol 1955; 59: 291–311.

    CAS  Google Scholar 

  36. Higashi T, Ito K, Nishikawa Y et al. Gallium-67 imaging in the evlauation of thyroid malignancy. Clin Nucl Med 1988; 13: 792–799.

    Article  PubMed  CAS  Google Scholar 

  37. Perloff WH, Schneeberg NG. Problem of thyroid carcinoma. Surgery 1951; 29: 572–580.

    PubMed  CAS  Google Scholar 

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Authors
  1. David K. Sirota
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Editors and Affiliations

  1. Division of Endocrinology, Mount Sinai Medical Center, New York, NY, USA

    Rhoda H. Cobin M.D. (Associate Clinical Professor of Medicine and Endocrinology, Mt. Sinai School of Medicine; Associate Attending Physician, Mt. Sinai Hospital) & David King Sirota M.D. (Associate Clinical Professor of Medicine and Endocrinology, Mt. Sinai School of Medicine; Associate Attending Physician, Mt. Sinai Hospital; Attending Endocrinologist, Jewish Home and Hospital for Aged) (Associate Clinical Professor of Medicine and Endocrinology, Mt. Sinai School of Medicine; Associate Attending Physician, Mt. Sinai Hospital) &  (Associate Clinical Professor of Medicine and Endocrinology, Mt. Sinai School of Medicine; Associate Attending Physician, Mt. Sinai Hospital; Attending Endocrinologist, Jewish Home and Hospital for Aged)

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© 1992 Springer-Verlag New York Inc.

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Sirota, D.K. (1992). Carcinoma Metastatic to the Thyroid Gland. In: Cobin, R.H., Sirota, D.K. (eds) Malignant Tumors of the Thyroid. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9127-2_11

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  • DOI: https://doi.org/10.1007/978-1-4613-9127-2_11

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-9129-6

  • Online ISBN: 978-1-4613-9127-2

  • eBook Packages: Springer Book Archive

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